Starzyńska Teresa, Londzin-Olesik Magdalena, Bałdys-Waligórska Agata, Bednarczuk Tomasz, Blicharz-Dorniak Jolanta, Bolanowski Marek, Boratyn-Nowicka Agnieszka, Borowska Małgorzata, Cichocki Andrzej, Ćwikła Jarosław B, Deptała Andrzej, Falconi Massimo, Foltyn Wanda, Handkiewicz-Junak Daria, Hubalewska-Dydejczyk Alicja, Jarząb Barbara, Junik Roman, Kajdaniuk Dariusz, Kamiński Grzegorz, Kolasińska-Ćwikła Agnieszka, Kowalska Aldona, Król Robert, Królicki Leszek, Kunikowska Jolanta, Kuśnierz Katarzyna, Lampe Paweł, Lange Dariusz, Lewczuk-Myślicka Anna, Lewiński Andrzej, Lipiński Michał, Marek Bogdan, Nasierowska-Guttmejer Anna, Nowakowska-Duława Ewa, Pilch-Kowalczyk Joanna, Remiszewski Piotr, Rosiek Violetta, Ruchała Marek, Siemińska Lucyna, Sowa-Staszczak Anna, Steinhof-Radwańska Katarzyna, Strzelczyk Janusz, Sworczak Krzysztof, Syrenicz Anhelli, Szawłowski Andrzej, Szczepkowski Marek, Wachuła Ewa, Zajęcki Wojciech, Zemczak Anna, Zgliczyński Wojciech, Kos-Kudła Beata
Endokrynol Pol. 2017;68(2):250-260. doi: 10.5603/EP.2017.0019.
Neuroendocrine neoplasms/tumours (NENs/NETs) of the large intestine are detected increasingly often, especially rectal tumours, which is probably associated with the widespread use of screening colonoscopy. There is a growing body of evidence supporting the thesis that the NENs of the rectum and the NENs of the colon are two different diseases. Rectal NENs are usually small lesions, of low to moderate histological malignancy, associated with good prognosis, and most may be treated endoscopically. NENs of the colon, however, are often aggressive, poorly differentiated, associated with a poor or uncer-tain prognosis, and require surgical treatment. The management guidelines regarding these groups of patients are constantly changing. On the basis of the recent literature data and conclusions reached by the working meeting of the Polish Network of Neuroendocrine Tumours (December 2016), this study completes and updates the data and management guidelines regarding colorectal NENs published in Endokrynologia Polska 2013; 64: 358-368.
大肠神经内分泌肿瘤（NENs/NETs）的检出率越来越高，尤其是直肠肿瘤，这可能与结肠镜筛查的广泛应用有关。越来越多的证据支持直肠NENs和结肠NENs是两种不同疾病的观点。直肠NENs通常为小病灶，组织学恶性程度低至中度，预后良好，大多数可通过内镜治疗。然而，结肠NENs往往具有侵袭性，分化差，预后不良或不确定，需要手术治疗。针对这两类患者的管理指南也在不断变化。基于波兰神经内分泌肿瘤网络工作会议（2016年12月）的最新文献数据和结论，本研究完善并更新了发表于《波兰内分泌学》2013年；64：358 - 368的关于结直肠NENs的数据和管理指南。
