Bertoglia María P, Gormaz Juan G, Libuy Matías, Sanhueza Dérgica, Gajardo Abraham, Srur Andrea, Wallbaum Magdalena, Erazo Marcia
Public Health Nutrition Program, School of Public Health, University of Chile, Santiago, Chile.
Molecular and Clinical Pharmacology Program, Bio-Medical Sciences Institute, University of Chile, Santiago, Chile.
PLoS One. 2017 May 25;12(5):e0178092. doi: 10.1371/journal.pone.0178092. eCollection 2017.
To estimate the impact of tobacco use, sedentary lifestyle, obesity and alcohol consumption on type 2 diabetes mellitus (T2DM) prevalence in the Chilean population.
The study-included 5,293 subjects with fasting glycaemia levels from the nationwide cross-sectional health survey in 2010, commissioned by the Ministry of Health, Chile. Crude and Adjusted Odds Ratio to T2DM and its corresponding 95% confidence interval were estimated through logistic regressions. Attributable fractions and population attributable fractions were estimated.
T2DM prevalence was 9.5%. Sedentary lifestyles and obesity were significant risk factors for T2DM. 52,4% of T2DM could be avoided if these individuals were not obese, and at a population level, 23% of T2DM could be preventable if obesity did not exist. A 64% of T2DM is explained by sedentariness, and if people would become active, a 62,2% of the cases of diabetes could be avoided.
About 79% of T2DM cases in Chile could be prevented with cost-effective strategies focused on preventing sedentary lifestyle and obesity. It's therefore urgent to implement evidence-based public health polices, aimed to decrease the prevalence of T2DM, by controlling its risk factors and consequently, reducing the complications from T2DM.
评估烟草使用、久坐不动的生活方式、肥胖和饮酒对智利人群2型糖尿病(T2DM)患病率的影响。
该研究纳入了5293名来自2010年全国横断面健康调查的空腹血糖水平受试者,该调查由智利卫生部委托进行。通过逻辑回归估计T2DM的粗比值比和调整后比值比及其相应的95%置信区间。估计归因分数和人群归因分数。
T2DM患病率为9.5%。久坐不动的生活方式和肥胖是T2DM的重要危险因素。如果这些个体不肥胖,52.4%的T2DM病例可以避免,在人群层面,如果不存在肥胖,23%的T2DM病例可以预防。64%的T2DM可归因于久坐,如果人们变得活跃,62.2%的糖尿病病例可以避免。
通过以预防久坐不动的生活方式和肥胖为重点的具有成本效益的策略,可以预防智利约79%的T2DM病例。因此,迫切需要实施基于证据的公共卫生政策,旨在通过控制T2DM的危险因素并因此减少T2DM的并发症来降低T2DM的患病率。