Suppr超能文献

肥胖、久坐不动的生活方式以及烟草和酒精消费对2型糖尿病患病率的人群影响:2010年智利一项健康人群调查分析

The population impact of obesity, sedentary lifestyle, and tobacco and alcohol consumption on the prevalence of type 2 diabetes: Analysis of a health population survey in Chile, 2010.

作者信息

Bertoglia María P, Gormaz Juan G, Libuy Matías, Sanhueza Dérgica, Gajardo Abraham, Srur Andrea, Wallbaum Magdalena, Erazo Marcia

机构信息

Public Health Nutrition Program, School of Public Health, University of Chile, Santiago, Chile.

Molecular and Clinical Pharmacology Program, Bio-Medical Sciences Institute, University of Chile, Santiago, Chile.

出版信息

PLoS One. 2017 May 25;12(5):e0178092. doi: 10.1371/journal.pone.0178092. eCollection 2017.

Abstract

AIM

To estimate the impact of tobacco use, sedentary lifestyle, obesity and alcohol consumption on type 2 diabetes mellitus (T2DM) prevalence in the Chilean population.

METHODS

The study-included 5,293 subjects with fasting glycaemia levels from the nationwide cross-sectional health survey in 2010, commissioned by the Ministry of Health, Chile. Crude and Adjusted Odds Ratio to T2DM and its corresponding 95% confidence interval were estimated through logistic regressions. Attributable fractions and population attributable fractions were estimated.

RESULTS

T2DM prevalence was 9.5%. Sedentary lifestyles and obesity were significant risk factors for T2DM. 52,4% of T2DM could be avoided if these individuals were not obese, and at a population level, 23% of T2DM could be preventable if obesity did not exist. A 64% of T2DM is explained by sedentariness, and if people would become active, a 62,2% of the cases of diabetes could be avoided.

INTERPRETATION

About 79% of T2DM cases in Chile could be prevented with cost-effective strategies focused on preventing sedentary lifestyle and obesity. It's therefore urgent to implement evidence-based public health polices, aimed to decrease the prevalence of T2DM, by controlling its risk factors and consequently, reducing the complications from T2DM.

摘要

目的

评估烟草使用、久坐不动的生活方式、肥胖和饮酒对智利人群2型糖尿病(T2DM)患病率的影响。

方法

该研究纳入了5293名来自2010年全国横断面健康调查的空腹血糖水平受试者,该调查由智利卫生部委托进行。通过逻辑回归估计T2DM的粗比值比和调整后比值比及其相应的95%置信区间。估计归因分数和人群归因分数。

结果

T2DM患病率为9.5%。久坐不动的生活方式和肥胖是T2DM的重要危险因素。如果这些个体不肥胖,52.4%的T2DM病例可以避免,在人群层面,如果不存在肥胖,23%的T2DM病例可以预防。64%的T2DM可归因于久坐,如果人们变得活跃,62.2%的糖尿病病例可以避免。

解读

通过以预防久坐不动的生活方式和肥胖为重点的具有成本效益的策略,可以预防智利约79%的T2DM病例。因此,迫切需要实施基于证据的公共卫生政策,旨在通过控制T2DM的危险因素并因此减少T2DM的并发症来降低T2DM的患病率。

相似文献

8
[Factors associated with sedentary lifestyle and physical inactivity in Chile: a qualitative systematic review].
Rev Med Chil. 2020 Feb;148(2):233-241. doi: 10.4067/s0034-98872020000200233.
9
Alcohol consumption and incidence of type 2 diabetes. Results from the CoLaus study.
Nutr Metab Cardiovasc Dis. 2015 Jan;25(1):75-84. doi: 10.1016/j.numecd.2014.08.010. Epub 2014 Sep 16.
10
Body mass index and type 2 diabetes in Thai adults: defining risk thresholds and population impacts.
BMC Public Health. 2017 Sep 15;17(1):707. doi: 10.1186/s12889-017-4708-7.

引用本文的文献

2
The Global Prevalence of Sedentary Time in Diabetes and Metabolic Syndrome: A Systematic Review and Meta-Analysis.
Iran J Public Health. 2024 Sep;53(9):2020-2029. doi: 10.18502/ijph.v53i9.16455.
6
Physical activity, sedentary behavior, and the risk of type 2 diabetes: A two-sample Mendelian Randomization analysis in the European population.
Front Endocrinol (Lausanne). 2022 Nov 3;13:964132. doi: 10.3389/fendo.2022.964132. eCollection 2022.
7
Effect of methylpyrazoles and coumarin association on the growth of Gram-negative bacteria.
Arch Microbiol. 2022 Feb 3;204(3):160. doi: 10.1007/s00203-022-02773-5.
8
Protective Effects of Iridoid Glycoside from Corni Fructus on Type 2 Diabetes with Nonalcoholic Fatty Liver in Mice.
Biomed Res Int. 2021 Jan 20;2021:3642463. doi: 10.1155/2021/3642463. eCollection 2021.

本文引用的文献

2
Fatty acid metabolism, energy expenditure and insulin resistance in muscle.
J Endocrinol. 2014 Jan 15;220(2):T61-79. doi: 10.1530/JOE-13-0397. Print 2014 Feb.
3
The many faces of diabetes: a disease with increasing heterogeneity.
Lancet. 2014 Mar 22;383(9922):1084-94. doi: 10.1016/S0140-6736(13)62219-9. Epub 2013 Dec 3.
4
Liver fat has a stronger association with risk factors for type 2 diabetes in African-American compared with Hispanic adolescents.
J Clin Endocrinol Metab. 2013 Sep;98(9):3748-54. doi: 10.1210/jc.2013-1138. Epub 2013 Jul 19.
6
Mechanisms of insulin resistance in obesity.
Front Med. 2013 Mar;7(1):14-24. doi: 10.1007/s11684-013-0262-6. Epub 2013 Mar 9.
7
Molecular mechanisms of insulin resistance in diabetes.
Adv Exp Med Biol. 2012;771:240-51. doi: 10.1007/978-1-4614-5441-0_19.
8
Signaling molecules involved in lipid-induced pancreatic beta-cell dysfunction.
DNA Cell Biol. 2013 Feb;32(2):41-9. doi: 10.1089/dna.2012.1874.
9
Glucocorticoids and type 2 diabetes: from physiology to pathology.
J Nutr Metab. 2012;2012:525093. doi: 10.1155/2012/525093. Epub 2012 Dec 18.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验