Nganvongpanit Korakot, Soponteerakul Ratsadakorn, Kaewkumpai Piyatida, Punyapornwithaya Veerasak, Buddhachat Kittisak, Nomsiri Raksiri, Kaewmong Patcharaporn, Kittiwatanawong Kongkiat, Chawangwongsanukun Rachanchai, Angkawanish Taweepoke, Thitaram Chatchote, Mahakkanukrauh Pasuk
Animal Bone and Joint Research Laboratory, Department of Veterinary Biosciences and Public Health, Faculty of Veterinary Medicine, Chiang Mai University, Chiang Mai, Thailand.
Department of Food Animal Clinic, Faculty of Veterinary Medicine, Chiang Mai University, Chiang Mai, Thailand.
J Anat. 2017 Jul;231(1):140-155. doi: 10.1111/joa.12620. Epub 2017 May 23.
The occurrence of osteoarthritis (OA) in marine mammals is still questionable. Here we investigated the prevalence of OA in marine (dolphin and dugong) and terrestrial mammals (Asian elephant, Asiatic buffalo, camel, cat, cattle, deer, dog, domestic goat, horse, human, hyena, impala, lion, Malayan tapir, Assam macaque, mule, pig, rabbit, red kangaroo, sheep, tiger and waterbuck). Skeletal remains obtained from five institutes were used as subjects; a total of 45 different parts (locations) of bones were observed for OA lesions. The prevalence of OA was reported as number of OA lesions/total number of bones. Our results revealed that the presence of OA in marine species (dolphin and dugong) was 2.44% and 3.33%, respectively. In dolphins, the highest OA occurrence was on the left and right humeral trochlea, with 13.68% and 12.63%, respectively, while the highest number of OA lesions in dugongs was on the lumbar vertebrae (8.79%). No significant difference (P > 0.05) in the prevalence of OA between sexes in dolphins and dugongs was observed, but we found a significant difference (P < 0.05) in 24 bone locations of human bones, which had the highest OA prevalence (48.93%), followed by dogs (3.94%). In conclusion, OA can occur in marine mammals, similar to terrestrial mammals, even though their natural habitat is the ocean.
海洋哺乳动物中骨关节炎（OA）的发生情况仍存在疑问。在此，我们调查了海洋哺乳动物（海豚和儒艮）以及陆地哺乳动物（亚洲象、亚洲水牛、骆驼、猫、牛、鹿、狗、家山羊、马、人类、鬣狗、黑斑羚、狮子、马来貘、阿萨姆猕猴、骡子、猪、兔子、红袋鼠、绵羊、老虎和水羚）中OA的患病率。从五个机构获取的骨骼遗骸用作研究对象；共观察了45个不同骨骼部位（位置）的OA病变情况。OA的患病率以OA病变数量/骨骼总数来报告。我们的结果显示，海洋物种（海豚和儒艮）中OA的存在率分别为2.44%和3.33%。在海豚中，OA发生率最高的部位是左右肱骨滑车，分别为13.68%和12.63%，而儒艮中OA病变数量最多的部位是腰椎（8.79%）。在海豚和儒艮中，未观察到两性之间OA患病率的显著差异（P>0.05），但我们发现人类骨骼的24个部位存在显著差异（P<0.05），其OA患病率最高（48.93%），其次是狗（3.94%）。总之，尽管海洋哺乳动物的自然栖息地是海洋，但OA也会在它们身上发生，这与陆地哺乳动物类似。
