Shirman G a, Graevskaia N a, Lavrova I K, Ginevskaia V A, Baeva L E
Vopr Virusol. 1988 Nov-Dec;33(6):725-9.
Antibodies from the yolk of eggs of chicken immunized with enteric viruses (simian rotavirus SA 11, poliomyelitis virus type 2, and Coxsackie B2) were obtained. The time course of the emergence and amplification of antibody in the yolk was followed for several months by neutralization tests and enzyme immunoassay. The long-term persistence of a high antibody level in the yolk, the simplicity of generation of large amounts of chromatographically pure preparations, as well as specificity of chicken immunoglobulins open ways for their employment in different test systems for the detection and identification of enteric viruses.
从用肠道病毒（猴轮状病毒SA 11、2型脊髓灰质炎病毒和柯萨奇B2病毒）免疫的鸡的蛋黄中获得了抗体。通过中和试验和酶免疫测定法，对蛋黄中抗体出现和扩增的时间进程进行了数月的跟踪。蛋黄中高抗体水平的长期持续存在、大量色谱纯制剂生成的简便性以及鸡免疫球蛋白的特异性，为其在不同检测系统中用于检测和鉴定肠道病毒开辟了道路。
