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作为治疗皮肤疾病潜在抗菌剂的商业精油

Commercial Essential Oils as Potential Antimicrobials to Treat Skin Diseases.

作者信息

Orchard Ané, van Vuuren Sandy

机构信息

Department of Pharmacy and Pharmacology, Faculty of Health Sciences, University of the Witwatersrand, 7 York Road, Parktown 2193, South Africa.

出版信息

Evid Based Complement Alternat Med. 2017;2017:4517971. doi: 10.1155/2017/4517971. Epub 2017 May 4.

Abstract

Essential oils are one of the most notorious natural products used for medical purposes. Combined with their popular use in dermatology, their availability, and the development of antimicrobial resistance, commercial essential oils are often an option for therapy. At least 90 essential oils can be identified as being recommended for dermatological use, with at least 1500 combinations. This review explores the fundamental knowledge available on the antimicrobial properties against pathogens responsible for dermatological infections and compares the scientific evidence to what is recommended for use in common layman's literature. Also included is a review of combinations with other essential oils and antimicrobials. The minimum inhibitory concentration dilution method is the preferred means of determining antimicrobial activity. While dermatological skin pathogens such as have been well studied, other pathogens such as , , , and species have been sorely neglected. Combination studies incorporating oil blends, as well as interactions with conventional antimicrobials, have shown that mostly synergy is reported. Very few viral studies of relevance to the skin have been made. Encouragement is made for further research into essential oil combinations with other essential oils, antimicrobials, and carrier oils.

摘要

精油是用于医疗目的的最臭名昭著的天然产品之一。鉴于它们在皮肤科的广泛应用、可得性以及抗菌耐药性的发展,商业精油常常是一种治疗选择。至少有90种精油被确定为推荐用于皮肤科,组合至少有1500种。本综述探讨了有关针对引起皮肤感染的病原体的抗菌特性的现有基础知识,并将科学证据与普通大众文献中推荐使用的内容进行比较。还包括对与其他精油和抗菌剂组合的综述。最低抑菌浓度稀释法是确定抗菌活性的首选方法。虽然诸如 等皮肤科皮肤病原体已得到充分研究,但诸如 、 、 和 属等其他病原体却被严重忽视。纳入精油混合物的组合研究以及与传统抗菌剂的相互作用表明,大多报告有协同作用。与皮肤相关的病毒研究非常少。鼓励进一步研究精油与其他精油、抗菌剂和载体油的组合。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ecc/5435909/95c5a31574a8/ECAM2017-4517971.001.jpg

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