Paturi Gunaranjan, Butts Christine A, Bentley-Hewitt Kerry L
The New Zealand Institute for Plant and Food Research Limited, Private Bag 92169, Auckland, 1142, New Zealand.
The New Zealand Institute for Plant and Food Research Limited, Private Bag 11600, Palmerston North, 4442, New Zealand.
Plant Foods Hum Nutr. 2017 Sep;72(3):321-323. doi: 10.1007/s11130-017-0614-5.
This study investigated the impact of diets containing various levels of avocado (5, 10 and 15%) on gut health in rats fed for six weeks. Avocado-fed rats had significantly higher food intakes while their body weights remained similar to the control diet-fed rats. No significant changes in intestinal bacterial populations (ileum, cecum and colon) were found in rats fed avocado diets compared to the control diet. Ileum and colon tissues of rats fed avocado diets showed significantly higher expression of genes (β-defensin 1, mucin 3 or mucin 4) and a greater number of mucin-producing goblet cells in the colon. The percentage of avocado in the diet had varying effects in altering the biomarkers, whereby diet containing 15% avocado was the more effective diet. This study delivers new knowledge on the role of avocado on gut health in rats.
本研究调查了含有不同水平牛油果（5%、10%和15%）的饮食对喂食六周的大鼠肠道健康的影响。喂食牛油果的大鼠食物摄入量显著更高，而它们的体重与喂食对照饮食的大鼠相似。与对照饮食相比，喂食牛油果饮食的大鼠肠道细菌群落（回肠、盲肠和结肠）未发现显著变化。喂食牛油果饮食的大鼠的回肠和结肠组织显示出基因（β-防御素1、粘蛋白3或粘蛋白4）的表达显著更高，并且结肠中产生粘蛋白的杯状细胞数量更多。饮食中牛油果的百分比在改变生物标志物方面有不同的影响，其中含有15%牛油果的饮食是更有效的饮食。本研究提供了关于牛油果对大鼠肠道健康作用的新知识。
