Pineda-Lozano Jessica Elizabeth, Martínez-Moreno Alma Gabriela, Virgen-Carrillo Carmen Alejandrina
Instituto de Investigaciones en Comportamiento Alimentario y Nutrición (IICAN), Centro Universitario del Sur, Universidad de Guadalajara, Ciudad Guzmán, Mexico.
Front Nutr. 2021 Feb 16;8:637183. doi: 10.3389/fnut.2021.637183. eCollection 2021.
Ischemic heart disease and stroke are two main causes of death that have prevailed for more than 15 years. Dyslipidemia and its parameters like hypercholesterolemia, hypertriglyceridemia, increase in low-density cholesterol, and a reduction of high-density cholesterol have been related with heart disease and risk of stroke. Approaches to improve the health and specifically reduce the risk of heart disease, such as medications and dietary interventions have been effective, but there are other potential sources of biological compounds that could have an effect due to their antioxidant properties. Avocado is a commonly consumed fruit especially its pulp, while the peel, seed, and leaf are usually discarded as waste. Some researchers have reported antioxidant, hepatoprotective, gastroprotective, lipid-lowering, and hypoglycemic effects in these wastes. In this review article, we have summarized the current evidence on the effect of biological compounds from avocado waste on dyslipidemia parameters in preclinical models. Also, we have included the compound extracted and the extraction method from the selected articles.
缺血性心脏病和中风是15年多来一直存在的两大主要死因。血脂异常及其参数，如高胆固醇血症、高甘油三酯血症、低密度胆固醇升高和高密度胆固醇降低，都与心脏病和中风风险有关。改善健康状况，特别是降低心脏病风险的方法，如药物治疗和饮食干预，已经取得了成效，但还有其他潜在的生物化合物来源，因其抗氧化特性可能会产生作用。鳄梨是一种常见的食用水果，尤其是其果肉，而果皮、果核和树叶通常作为废弃物丢弃。一些研究人员报告了这些废弃物具有抗氧化、保肝、胃保护、降血脂和降血糖作用。在这篇综述文章中，我们总结了目前关于鳄梨废弃物中的生物化合物对临床前模型血脂异常参数影响的证据。此外，我们还纳入了所选文章中提取的化合物和提取方法。
