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老年人肌肉减少症与身体活动之间的关系：一项系统评价和荟萃分析。

Relationship between sarcopenia and physical activity in older people: a systematic review and meta-analysis.

作者信息

Steffl Michal, Bohannon Richard W, Sontakova Lenka, Tufano James J, Shiells Kate, Holmerova Iva

机构信息

Department of Physiology and Biochemistry, Faculty of Physical Education and Sport, Charles University Prague, Prague, Czech Republic.

Department of Physical Therapy, College of Pharmacy and Health Sciences, Campbell University, Buies Creek, NC, USA.

出版信息

Clin Interv Aging. 2017 May 17;12:835-845. doi: 10.2147/CIA.S132940. eCollection 2017.

DOI:10.2147/CIA.S132940
PMID:28553092
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5441519/
Abstract

Physical activity (PA) has been identified as beneficial for many diseases and health disorders, including sarcopenia. The positive influence of PA interventions on sarcopenia has been described previously on many occasions. Current reviews on the topic include studies with varied PA interventions for sarcopenia; nevertheless, no systematic review exploring the effects of PA in general on sarcopenia has been published. The main aim of this study was to explore the relationship between PA and sarcopenia in older people on the basis of cross-sectional and cohort studies. We searched PubMed, Scopus, EBSCO, and ScienceDirect for articles addressing the relationship between PA and sarcopenia. Twenty-five articles were ultimately included in the qualitative and quantitative syntheses. A statistically significant association between PA and sarcopenia was documented in most of the studies, as well as the protective role of PA against sarcopenia development. Furthermore, the meta-analysis indicated that PA reduces the odds of acquiring sarcopenia in later life (odds ratio [OR] =0.45; 95% confidence interval [CI] 0.37-0.55). The results of this systematic review and meta-analysis confirm the beneficial influence of PA in general for the prevention of sarcopenia.

摘要

体育活动（PA）已被确认为对包括肌肉减少症在内的多种疾病和健康问题有益。此前已有多次描述PA干预对肌肉减少症的积极影响。目前关于该主题的综述包括针对肌肉减少症的各种PA干预研究；然而，尚未发表过探索PA总体上对肌肉减少症影响的系统综述。本研究的主要目的是基于横断面研究和队列研究，探讨老年人中PA与肌肉减少症之间的关系。我们在PubMed、Scopus、EBSCO和ScienceDirect上搜索了探讨PA与肌肉减少症关系的文章。最终有25篇文章被纳入定性和定量综合分析。大多数研究都记录了PA与肌肉减少症之间具有统计学意义的关联，以及PA对肌肉减少症发展的保护作用。此外，荟萃分析表明，PA可降低晚年患肌肉减少症的几率（优势比[OR]=0.45；95%置信区间[CI]0.37 - 0.55）。该系统综述和荟萃分析的结果证实了PA总体上对预防肌肉减少症具有有益影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c08/5441519/933d5b314f61/cia-12-835Fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c08/5441519/20498b9e548a/cia-12-835Fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c08/5441519/b237203908b1/cia-12-835Fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c08/5441519/83d1ec7e80b7/cia-12-835Fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c08/5441519/933d5b314f61/cia-12-835Fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c08/5441519/20498b9e548a/cia-12-835Fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c08/5441519/b237203908b1/cia-12-835Fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c08/5441519/83d1ec7e80b7/cia-12-835Fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c08/5441519/933d5b314f61/cia-12-835Fig4.jpg

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