乳头瘤病毒相关癌症中的病毒癌基因和细胞癌基因。
Viral and cellular oncogenes in papillomavirus-associated cancers.
作者信息
Campo M S
机构信息
Beatson Institute for Cancer Research, Bearsden, Glasgow, UK.
出版信息
Br J Cancer Suppl. 1988 Dec;9:80-4.
Abstract
Papillomaviruses are one of several factors implicated in the aetiology of squamous cell carcinomas both in man and in animals. Their potential for malignant transformation is fully expressed when co-operation takes place between viral functions, cellular functions and chemical or physical co-carcinogens. This review presents a brief description of the viral transforming genes and of the cellular genes involved in transformation, and attempts to analyse how the co-operation between the two sets of genes is achieved.
摘要
乳头瘤病毒是人与动物鳞状细胞癌病因中涉及的多种因素之一。当病毒功能、细胞功能与化学或物理共致癌物之间发生协同作用时，它们的恶性转化潜能就会充分显现。本文简要介绍了病毒转化基因以及参与转化的细胞基因，并试图分析这两组基因之间的协同作用是如何实现的。
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