Inkster T, Ferguson K, Edwardson A, Gunson R, Soutar R
Department of Infection Control, Gartnavel General Hospital, Glasgow, UK.
Department of Infection Control, Gartnavel General Hospital, Glasgow, UK.
J Hosp Infect. 2017 Aug;96(4):353-359. doi: 10.1016/j.jhin.2017.05.002. Epub 2017 May 6.
Respiratory syncytial virus (RSV) causes significant respiratory tract infection in immunosuppressed patients.
To describe two consecutive yearly outbreaks of RSV in our haemato-oncology ward.
Haematology patients presenting with respiratory symptoms were screened by polymerase chain reaction for viral respiratory pathogens using a saline gargle.
None of our patients had undergone bone marrow transplant but all had underlying haematological malignancies. Eight patients were affected in the first outbreak (mortality rate: 37.5%) and 12 patients were affected in the second (mortality rate: 8.3%). Extensive infection control measures were implemented in both outbreaks and were successful in preventing further cross-transmission.
There was significant learning from both outbreaks and actions implemented with the aim of reducing the likelihood and impact of future outbreaks.
呼吸道合胞病毒（RSV）在免疫抑制患者中可引起严重的呼吸道感染。
描述我们血液肿瘤病房连续两年每年发生的RSV暴发情况。
对出现呼吸道症状的血液学患者，采用盐水漱口法进行聚合酶链反应筛查病毒呼吸道病原体。
我们的患者均未接受过骨髓移植，但均患有潜在的血液系统恶性肿瘤。第一次暴发中有8名患者受影响（死亡率：37.5%），第二次有12名患者受影响（死亡率：8.3%）。两次暴发均实施了广泛的感染控制措施，成功防止了进一步的交叉传播。
从这两次暴发以及为降低未来暴发的可能性和影响而采取的行动中获得了重要经验。
