Borkum Dana B, Temes Christina M, Magni Laura R, Fitzmaurice Garrett M, Aguirre Blaise A, Goodman Marianne, Zanarini Mary C
McLean Hospital, Belmont, MA, USA.
Department of Psychiatry, Harvard Medical School, Boston, MA, USA.
Personal Ment Health. 2017 Aug;11(3):189-194. doi: 10.1002/pmh.1380. Epub 2017 May 28.
Existing literature on the aetiology of borderline personality disorder (BPD) has primarily focused on pathological childhood experiences, while little to no research has been conducted on protective factors that may serve to ameliorate these symptoms. The current study attempts to fill this gap in the literature by comparing the rates of childhood protective factors among adolescents with BPD, psychiatrically healthy adolescents and adults with BPD.
One hundred and four subjects were adolescent inpatients between the ages of 13 and 17 who met Revised Diagnostic Interview for Borderlines and Diagnostic and Statistical Manual of Mental Disorders Fourth Edition criteria for BPD. Sixty were age-matched psychiatrically healthy comparison subjects. Two hundred and ninety subjects were adult inpatients between the ages of 18 and 35 who met Revised Diagnostic Interview for Borderlines and Revised Diagnostic and Statistical Manual of Mental Disorders Third Edition criteria for BPD. All three groups were interviewed by using the Revised Childhood Experiences Questionnaire, a semi-structured interview that assesses pathological and protective childhood experiences.
Psychiatrically healthy adolescents reported significantly higher rates of 4 out of 18 protective factors than adolescents with BPD. Adolescents with BPD reported significantly higher rates of 5 of these 18 protective factors than adults with BPD. Adults with BPD were significantly more likely to endorse having a steady after school or weekend work record than adolescents with BPD.
Taken together, the results of this study suggest that adolescents meeting criteria for BPD report lower rates of some protective factors than psychiatrically healthy adolescents. They also suggest that they have higher rates of some protective factors than adults with BPD. Copyright © 2017 John Wiley & Sons, Ltd.
关于边缘型人格障碍（BPD）病因的现有文献主要集中在病理性童年经历上，而对于可能有助于缓解这些症状的保护因素的研究极少甚至没有。本研究试图通过比较BPD青少年、精神健康青少年以及BPD成年患者童年保护因素的发生率来填补这一文献空白。
104名受试者为年龄在13至17岁之间的青少年住院患者，他们符合《边缘型人格障碍修订诊断访谈》以及《精神障碍诊断与统计手册》第四版中BPD的诊断标准。60名是年龄匹配的精神健康对照受试者。290名受试者为年龄在18至35岁之间的成年住院患者，他们符合《边缘型人格障碍修订诊断访谈》以及《精神障碍诊断与统计手册》第三版修订版中BPD的诊断标准。所有三组均通过使用《修订童年经历问卷》进行访谈，这是一种半结构化访谈，用于评估病理性和保护性童年经历。
精神健康青少年报告的18种保护因素中有4种的发生率显著高于BPD青少年。BPD青少年报告的这18种保护因素中有5种的发生率显著高于BPD成年患者。与BPD青少年相比，BPD成年患者更有可能认可自己有稳定的课后或周末工作记录。
总体而言，本研究结果表明，符合BPD标准的青少年报告的某些保护因素发生率低于精神健康青少年。研究结果还表明，他们报告的某些保护因素发生率高于BPD成年患者。版权所有© 2017约翰·威利父子有限公司。
