Lopez-Blanco Mercedes, Izaguirre-Espinoza Isbelia, Macias-Tomei Coromoto, Saab-Verardy Leonardo
Departamento de Tecnología de Procesos Biológicos y Bioquímicos, Universidad Simón Bolívar.
Departamento de Auxología, División de Investigaciones Biológicas, Fundacredesa.
Am J Hum Biol. 1995;7(4):517-527. doi: 10.1002/ajhb.1310070413.
A sample of 113 boys and 101 girls of the Caracas Mixed-Longitudinal Study was grouped into early, average, and late maturers according to selected cut-off points of the 10th and 90th centiles for age at peak height velocity (APHV). Individual curves were fitted with the cubic spline function, in which height velocity corresponds to the first derivative. Age at menarche (AM) was estimated by recall in a longitudinal context. Differences between groups were assessed with F and t-tests. Girls were approximately 2 years earlier than boys in APHV and thus significantly shorter; their estimated PHV was also significantly lower. APHV in boys and girls occurred 0.4-0.6 years earlier than in European children, which is consistent with a faster tempo of growth of Venezuelan youth. The three maturity groups differed significantly in timing, stature, and AM. Early maturers were taller than average maturers, and the latter were taller than late maturers with maximal differences between the extreme groups at ages 13-14 in boys and 11-12 in girls. Early maturers grew at a faster rate than average maturers, and the latter grew at a faster rate than late maturers up to 13 years in boys and 10-11 years in girls. Despite difficulties encountered in the analysis of mixed-linked longitudinal data, meaningful growth differences were found between maturity groups of urban Venezuelan children. © 1995 Wiley-Liss, Inc.
在加拉加斯混合纵向研究中,选取了113名男孩和101名女孩作为样本,根据身高增长速度峰值(APHV)年龄的第10和第90百分位数的选定切点,将他们分为早熟、平均成熟和晚熟三组。用三次样条函数拟合个体曲线,其中身高增长速度对应一阶导数。通过纵向背景下的回忆来估计初潮年龄(AM)。用F检验和t检验评估组间差异。女孩的APHV比男孩早约2年,因此明显更矮;她们估计的身高增长速度峰值也显著更低。男孩和女孩的APHV比欧洲儿童早0.4 - 0.6年,这与委内瑞拉青少年更快的生长节奏一致。这三个成熟组在时间、身高和初潮年龄方面存在显著差异。早熟者比平均成熟者高,平均成熟者比晚熟者高,在13 - 14岁的男孩和11 - 12岁的女孩中,极端组之间的差异最大。早熟者的生长速度比平均成熟者快,在男孩13岁之前和女孩10 - 11岁之前,平均成熟者的生长速度比晚熟者快。尽管在分析混合关联纵向数据时遇到困难,但在委内瑞拉城市儿童的成熟组之间发现了有意义的生长差异。© 1995威利 - 利斯公司。