Shabbir Muhmmad Asim, Khan Moazzam Rafiq, Saeed Muhammad, Pasha Imran, Khalil Anees Ahmed, Siraj Naila
National Institute of Food Science and Technology, University of Agriculture, Faisalabad, 38000, Pakistan.
Lipids Health Dis. 2017 May 30;16(1):99. doi: 10.1186/s12944-017-0489-3.
Punicic acid, a bioactive compound of pomegranate seed oil has gained wide attention for their therapeutic potential. Different studies conducted on animal and human models have revealed that punicic acid is very effective against various chronic diseases. Substantial laboratory works has been carried out to elaborate punicic acid effectiveness and mechanism of action in animals. The intention of this review article is to explore the facts about the clinical trials of punicic acid and to discuss different future strategies that can be employed to use it in human clinical trials. Although punicic acid may represent a novel therapeutic unconventional approach for some disorders, still further experimental studies are required to demonstrate its effects in human beings.
石榴酸是石榴籽油中的一种生物活性化合物,因其治疗潜力而受到广泛关注。在动物和人体模型上进行的不同研究表明,石榴酸对各种慢性疾病非常有效。已经开展了大量实验室工作来阐述石榴酸在动物体内的有效性和作用机制。这篇综述文章的目的是探讨石榴酸临床试验的相关事实,并讨论可用于人类临床试验的不同未来策略。尽管石榴酸可能代表了一种针对某些疾病的新型非常规治疗方法,但仍需要进一步的实验研究来证明其在人体中的效果。