State Key Laboratory for Advanced Metals and Materials, School of Materials Science and Engineering, University of Science and Technology Beijing , Beijing 100083, P. R. China.
State Key Laboratory of Fine Chemicals, Dalian University of Technology , Dalian 116024, P. R. China.
ACS Appl Mater Interfaces. 2017 Jun 21;9(24):20895-20903. doi: 10.1021/acsami.7b04956. Epub 2017 Jun 8.
Copper (Cu) nanoparticles possess unusual electrical, thermal, and optical properties. However, applications of these materials are often limited by their tendency to oxidize. We prepared Cu nanoparticles by a simple polyol method, with a good control over the particle size. The reaction required no inert atmosphere or surfactant agents. The as-prepared Cu nanoparticles showed good resistance to oxidation in solution. These Cu nanoparticles were then incorporated into a biocompatible polysaccharide hydrogel, which further stabilized the nanoparticles. The hybrid hydrogel exhibited a rapid self-healing ability. Because of the excellent photothermal conversion properties of the embedded Cu nanoparticles, the hybrid hydrogel showed rapid temperature elevation under laser irradiation. The hybrid hydrogel showed limited cytotoxicity; however, under laser irradiation the hydrogel displayed antibacterial properties owing to the heating effects. This study demonstrates that our hybrid hydrogel may have applications in biomedical fields and photothermal therapy.
铜（Cu）纳米粒子具有独特的电学、热学和光学性质。然而，这些材料的应用往往受到其易氧化的限制。我们通过简单的多元醇法制备了 Cu 纳米粒子，可以很好地控制粒径。该反应不需要惰性气氛或表面活性剂。所制备的 Cu 纳米粒子在溶液中表现出良好的抗氧化性。然后将这些 Cu 纳米粒子掺入到一种生物相容性多糖水凝胶中，进一步稳定了纳米粒子。该杂化水凝胶表现出快速的自修复能力。由于嵌入的 Cu 纳米粒子具有优异的光热转换性能，杂化水凝胶在激光照射下迅速升温。该杂化水凝胶表现出有限的细胞毒性；然而，在激光照射下，由于加热效应，水凝胶显示出抗菌性能。本研究表明，我们的杂化水凝胶可能在生物医学领域和光热治疗中有应用。
