一项比较生长抑素和血管加压素控制急性静脉曲张出血效果的前瞻性随机对照临床试验。
A prospective randomised controlled clinical trial comparing somatostatin and vasopressin in controlling acute variceal haemorrhage.
作者信息
Jenkins S A, Baxter J N, Corbett W, Devitt P, Ware J, Shields R
出版信息
Br Med J (Clin Res Ed). 1985 Jan 26;290(6464):275-8. doi: 10.1136/bmj.290.6464.275.
Abstract
Twenty two patients were entered into a randomised controlled clinical trial comparing the efficacy of somatostatin and vasopressin in controlling acute variceal haemorrhage. Somatostatin was significantly more successful in controlling acute variceal haemorrhage than vasopressin (p = 0.003). Furthermore, no complications were observed during treatment with somatostatin.
摘要
22名患者进入了一项随机对照临床试验，比较生长抑素和血管加压素在控制急性静脉曲张出血方面的疗效。生长抑素在控制急性静脉曲张出血方面比血管加压素显著更有效（p = 0.003）。此外，在生长抑素治疗期间未观察到并发症。
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本文引用的文献
1
Multiple infusions of posterior pituitary extract in the treatment of bleeding esophageal varices.
Ann Intern Med. 1962 Nov;57:804-9. doi: 10.7326/0003-4819-57-5-804.
2
3
[Results of conservatively treated upper arm fractures in adults (author's transl)].
Langenbecks Arch Chir. 1982;357(2):117-23. doi: 10.1007/BF01237457.
4
Comparison of intravenous somatostatin and vasopressin infusions in treatment of acute variceal hemorrhage.静脉输注生长抑素与血管加压素治疗急性静脉曲张出血的比较。
Hepatology. 1984 May-Jun;4(3):442-6. doi: 10.1002/hep.1840040315.
5
[Effects of somatostatin in oesophagal bleeding (author's transl)].
Nouv Presse Med. 1980 Mar 12;9(17):1225-7.
6
Effect of somatostatin on splanchnic hemodynamics in patients with cirrhosis of the liver and in normal subjects.生长抑素对肝硬化患者及正常受试者内脏血流动力学的影响。
Gastroenterology. 1981 Mar;80(3):526-32.
7
Effects of somatostatin on hepatic and systemic hemodynamics in patients with cirrhosis of the liver: comparison with vasopressin.生长抑素对肝硬化患者肝脏及全身血流动力学的影响：与血管加压素的比较。
Gastroenterology. 1981 Mar;80(3):518-25.
8
Somatostatin and cimetidine in peptic-ulcer haemorrhage. A randomised controlled trial.生长抑素与西咪替丁治疗消化性溃疡出血的随机对照试验。
Lancet. 1980 Apr 19;1(8173):844-6. doi: 10.1016/s0140-6736(80)91352-5.
9
Hypothalamic polypeptide that inhibits the secretion of immunoreactive pituitary growth hormone.抑制免疫反应性垂体生长激素分泌的下丘脑多肽。
Science. 1973 Jan 5;179(4068):77-9. doi: 10.1126/science.179.4068.77.
10
Inhibition of gastrin and gastric-acid secretion by growth-hormone release-inhibiting hormone.生长抑素对胃泌素及胃酸分泌的抑制作用
Lancet. 1974 Nov 9;2(7889):1106-9. doi: 10.1016/s0140-6736(74)90869-1.
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