Decelis Stephen, Sardella Davide, Triganza Thomas, Brincat Jean-Pierre, Gatt Ruben, Valdramidis Vasilis P
Mycology laboratory, Mater Dei Hospital, Msida, Malta.
Centre for Molecular Medicine and Biobanking, University of Malta, Msida, Malta.
R Soc Open Sci. 2017 May 3;4(5):161032. doi: 10.1098/rsos.161032. eCollection 2017 May.
Air filters support fungal growth, leading to generation of conidia and volatile organic compounds, causing allergies, infections and food spoilage. Filters that inhibit fungi are therefore necessary. Zinc oxide (ZnO) nanoparticles have anti-fungal properties and therefore are good candidates for inhibiting growth. Two concentrations (0.012 M and 0.12 M) were used to coat two types of filters (melt-blown and needle-punched) for three different periods (0.5, 5 and 50 min). and isolated from spoiled pears were used as test organisms. Conidial suspensions of 10 to 10 spores ml were prepared in Sabouraud dextrose agar at 50°C, and a modified slide-culture technique was used to test the anti-fungal properties of the filters. was the more sensitive organism, with inhibition at 0.012 M at only 0.5 min coating time on the needle-punched filter. The longer the coating time, the more effective inhibition was for both organisms. Furthermore, it was also determined that the coating process had only a slight effect on the Young's Moduli of the needle-punched filters, while the Young's Moduli of the melt-blown filters is more susceptible to the coating method. This work contributes to the assessment of the efficacy of filter coating with ZnO nanopaticles aimed at inhibiting fungal growth.
空气过滤器会促进真菌生长，导致分生孢子和挥发性有机化合物的产生，进而引发过敏、感染和食物变质。因此，需要能抑制真菌的过滤器。氧化锌（ZnO）纳米颗粒具有抗真菌特性，是抑制真菌生长的理想选择。使用两种浓度（0.012M和0.12M）对两种类型的过滤器（熔喷和针刺）进行三种不同时长（0.5、5和50分钟）的涂层处理。从腐烂梨中分离出的[具体名称未给出]用作测试生物。在50°C的沙氏葡萄糖琼脂培养基中制备10至10孢子/毫升的分生孢子悬浮液，并采用改良的载玻片培养技术来测试过滤器的抗真菌性能。[具体名称未给出]是更敏感的生物，在针刺过滤器上仅涂层0.5分钟、浓度为0.012M时就受到抑制。涂层时间越长，对两种生物的抑制效果越有效。此外，还确定涂层过程对针刺过滤器的杨氏模量影响较小，而熔喷过滤器的杨氏模量更容易受到涂层方法的影响。这项工作有助于评估用ZnO纳米颗粒对过滤器进行涂层以抑制真菌生长的效果。
