Haddad Anthony G, Giatsidis Giorgio, Orgill Dennis P, Halvorson Eric G
Department of Surgery, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115, USA.
Division of Plastic Surgery, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115, USA.
Clin Plast Surg. 2017 Jul;44(3):627-634. doi: 10.1016/j.cps.2017.02.019. Epub 2017 Apr 1.
Advancements in surgical wound treatment have led to skin substitutes and bioscaffolds as temporary and permanent coverage for burn wounds. Skin substitutes are used to improve wound coverage and restore the functional and aesthetic qualities of skin, and help to prevent wound infection and maintain a moist wound healing environment. Although allografts are preferred when autografts are not possible, high costs and limited availability have led to the use of xenografts and the development of skin substitutes and bioscaffolds. Despite constant evolution in the development of these skin substitutes and bioscaffolds, no single product stands out as the gold standard.
外科伤口治疗的进展催生了皮肤替代品和生物支架，用于烧伤创面的临时和永久覆盖。皮肤替代品用于改善创面覆盖，恢复皮肤的功能和美观特性，并有助于预防伤口感染，维持湿润的伤口愈合环境。尽管在无法进行自体移植时异体移植是首选，但高成本和有限的可获得性促使人们使用异种移植以及开发皮肤替代品和生物支架。尽管这些皮肤替代品和生物支架在不断发展，但没有一种产品能脱颖而出成为金标准。
