Saffle Jeffrey R
Department of Surgery, University of Utah Health Center, Salt Lake City, 84132, USA.
Clin Plast Surg. 2009 Oct;36(4):627-41. doi: 10.1016/j.cps.2009.05.005.
Prompt excision of major burn wounds has been repeatedly shown to improve survival, speed closure, and reduce infection. Immediate coverage with autograft skin is the preferred method of definitive closure of these wounds. However, when harvesting of donor skin is unavailable, or wounds are not ready for autografting, temporary closure with a variety of products can help reduce evaporative loss, prevent infection, and ameliorate pain and metabolic stress. Fresh cadaver allograft is the gold standard for such closure, but other products, including frozen cadaver skin, xenografts, and several synthetic products, are also available. This article reviews the physiology, and types of products, and their uses.
多次研究表明，及时切除大面积烧伤创面可提高生存率、加速创面愈合并减少感染。自体皮肤立即覆盖是这些创面确定性闭合的首选方法。然而，当无法获取供皮，或创面尚未准备好进行自体移植时，使用多种产品进行临时闭合有助于减少蒸发损失、预防感染并减轻疼痛和代谢应激。新鲜尸体同种异体皮是此类闭合的金标准，但也有其他产品可供选择，包括冷冻尸体皮肤、异种移植物和几种合成产品。本文综述了其生理学、产品类型及其用途。
