干细胞与组织工程：皮肤及其组成部分的再生
Stem Cells and Tissue Engineering: Regeneration of the Skin and Its Contents.
作者信息
Strong Amy L, Neumeister Michael W, Levi Benjamin
机构信息
Division of Plastic Surgery, Department of Surgery, University of Michigan, 1500 East Medical Center Drive, Ann Arbor, MI 48109, USA.
Department of Surgery, Institute for Plastic Surgery, Southern Illinois University School of Medicine, 747 North Rutledge Street, Springfield, IL 62702, USA.
出版信息
Clin Plast Surg. 2017 Jul;44(3):635-650. doi: 10.1016/j.cps.2017.02.020. Epub 2017 Apr 22.
Abstract
In this review, the authors discuss the stages of skin wound healing, the role of stem cells in accelerating skin wound healing, and the mechanism by which these stem cells may reconstitute the skin in the context of tissue engineering.
摘要
在这篇综述中，作者讨论了皮肤伤口愈合的阶段、干细胞在加速皮肤伤口愈合中的作用，以及在组织工程背景下这些干细胞可能重建皮肤的机制。
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本文引用的文献
1
Transplantation of an LGR6+ Epithelial Stem Cell-Enriched Scaffold for Repair of Full-Thickness Soft-Tissue Defects: The In Vitro Development of Polarized Hair-Bearing Skin.
Plast Reconstr Surg. 2016 Feb;137(2):495-507. doi: 10.1097/01.prs.0000475761.09451.00.
2
Stem Cells in Skin Regeneration, Wound Healing, and Their Clinical Applications.
Int J Mol Sci. 2015 Oct 23;16(10):25476-501. doi: 10.3390/ijms161025476.
3
Exosome-delivered microRNAs modulate the inflammatory response to endotoxin.
Nat Commun. 2015 Jun 18;6:7321. doi: 10.1038/ncomms8321.
4
Autologous Adipose Stromal Cells Seeded onto a Human Collagen Matrix for Dermal Regeneration in Chronic Wounds: Clinical Proof of Concept.
Plast Reconstr Surg. 2015 Aug;136(2):279-295. doi: 10.1097/PRS.0000000000001437.
5
Adipose stromal cells repair pressure ulcers in both young and elderly mice: potential role of adipogenesis in skin repair.
Stem Cells Transl Med. 2015 Jun;4(6):632-42. doi: 10.5966/sctm.2014-0235. Epub 2015 Apr 21.
6
Recipient wound bed characteristics affect scarring and skin graft contraction.
Wound Repair Regen. 2015 Mar-Apr;23(2):287-96. doi: 10.1111/wrr.12267.
7
Dermal matrices and bioengineered skin substitutes: a critical review of current options.
Plast Reconstr Surg Glob Open. 2015 Feb 6;3(1):e284. doi: 10.1097/GOX.0000000000000219. eCollection 2015 Jan.
8
Wound repair and regeneration: mechanisms, signaling, and translation.
Sci Transl Med. 2014 Dec 3;6(265):265sr6. doi: 10.1126/scitranslmed.3009337.
9
Fibroblasts and myofibroblasts in wound healing.
Clin Cosmet Investig Dermatol. 2014 Nov 6;7:301-11. doi: 10.2147/CCID.S50046. eCollection 2014.
10
Adipose-derived stem-cell-seeded non-cross-linked porcine acellular dermal matrix increases cellular infiltration, vascular infiltration, and mechanical strength of ventral hernia repairs.
Tissue Eng Part A. 2015 Feb;21(3-4):475-85. doi: 10.1089/ten.TEA.2014.0235. Epub 2014 Oct 2.
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