Center for Biomedical Imaging, Department of Radiology, New York University School of Medicine, New York, New York, USA.
Siemens Healthineers, New York, New York, USA.
J Magn Reson Imaging. 2018 Mar;47(3):723-728. doi: 10.1002/jmri.25779. Epub 2017 Jun 3.
To develop and test a deep learning approach named Convolutional Neural Network (CNN) for automated screening of T -weighted (T WI) liver acquisitions for nondiagnostic images, and compare this automated approach to evaluation by two radiologists.
We evaluated 522 liver magnetic resonance imaging (MRI) exams performed at 1.5T and 3T at our institution between November 2014 and May 2016 for CNN training and validation. The CNN consisted of an input layer, convolutional layer, fully connected layer, and output layer. 351 T WI were anonymized for training. Each case was annotated with a label of being diagnostic or nondiagnostic for detecting lesions and assessing liver morphology. Another independently collected 171 cases were sequestered for a blind test. These 171 T WI were assessed independently by two radiologists and annotated as being diagnostic or nondiagnostic. These 171 T WI were presented to the CNN algorithm and image quality (IQ) output of the algorithm was compared to that of two radiologists.
There was concordance in IQ label between Reader 1 and CNN in 79% of cases and between Reader 2 and CNN in 73%. The sensitivity and the specificity of the CNN algorithm in identifying nondiagnostic IQ was 67% and 81% with respect to Reader 1 and 47% and 80% with respect to Reader 2. The negative predictive value of the algorithm for identifying nondiagnostic IQ was 94% and 86% (relative to Readers 1 and 2).
We demonstrate a CNN algorithm that yields a high negative predictive value when screening for nondiagnostic T WI of the liver.
2 Technical Efficacy: Stage 2 J. Magn. Reson. Imaging 2018;47:723-728.
开发并测试一种名为卷积神经网络(CNN)的深度学习方法,用于自动筛选 T 加权(T WI)肝脏采集图像是否为非诊断性图像,并将这种自动方法与两名放射科医生的评估进行比较。
我们评估了 2014 年 11 月至 2016 年 5 月在我们机构进行的 522 例 1.5T 和 3T 肝脏磁共振成像(MRI)检查,用于 CNN 的训练和验证。CNN 由输入层、卷积层、全连接层和输出层组成。351 例 T WI 被匿名化用于训练。每个病例都被标记为有或无病变检测和肝脏形态评估的诊断性或非诊断性。另外还收集了 171 例独立的病例用于盲法测试。这 171 例 T WI 由两名放射科医生独立评估,并标记为诊断性或非诊断性。这 171 例 T WI 被提交给 CNN 算法,并比较算法的图像质量(IQ)输出与两名放射科医生的结果。
Reader 1 与 CNN 在 79%的病例中 IQ 标签一致,Reader 2 与 CNN 在 73%的病例中 IQ 标签一致。CNN 算法在识别非诊断性 IQ 方面的灵敏度和特异性分别为 67%和 81%(相对于 Reader 1)和 47%和 80%(相对于 Reader 2)。算法识别非诊断性 IQ 的阴性预测值分别为 94%和 86%(相对于 Reader 1 和 2)。
我们展示了一种 CNN 算法,在筛选肝脏非诊断性 T WI 时具有较高的阴性预测值。
2 技术功效:第 2 阶段 J. Magn. Reson. Imaging 2018;47:723-728.