Kandel Pujan, Wallace Michael B
Department of Gastroenterology and Hepatology, Mayo Clinic Florida, 4500 San Pablo Road, Jacksonville, FL 32224, USA.
Department of Gastroenterology and Hepatology, Mayo Clinic Florida, 4500 San Pablo Road, Jacksonville, FL 32224, USA.
Gastrointest Endosc Clin N Am. 2017 Jul;27(3):423-446. doi: 10.1016/j.giec.2017.02.007.
Advances in imaging technologies have demonstrated promise in early detection of dysplasia and cancer in Barrett's esophagus (BE). Optical chromoendoscopy, dye-based chromoendoscopy, and novel technologies have provided the opportunity to visualize the cellular and subcellular structures. Only narrow-band imaging and acetic acid chromoendoscopy have reached benchmarks for clinical use. Volumetric laser endomicroscopy and molecular imaging are not established for routine use. Best practice in management of BE should be focused on careful endoscopic examination, resection, or ablation of the entire abnormal lesion, as well as the use of available imaging technique that has good diagnostic accuracy.
成像技术的进步已在巴雷特食管(BE)发育异常和癌症的早期检测中显示出前景。光学色素内镜检查、基于染料的色素内镜检查和新技术提供了可视化细胞和亚细胞结构的机会。只有窄带成像和醋酸色素内镜检查达到了临床应用的标准。容积激光内镜显微镜检查和分子成像尚未确立常规应用。BE管理的最佳实践应侧重于仔细的内镜检查、切除或消融整个异常病变,以及使用具有良好诊断准确性的现有成像技术。