Costa Andressa Dias, Zerbini Maria Claudia Nogueira, Cristofani Lilian
Pathology Department - Hospital das Clínicas - Faculdade de Medicina - Universidade de São Paulo, São Paulo/SP - Brazil.
Pathology Department - Faculdade de Medicina - Universidade de São Paulo, São Paulo/SP - Brazil.
Autops Case Rep. 2014 Jun 30;4(2):27-33. doi: 10.4322/acr.2014.017. eCollection 2014 Apr-Jun.
Although neonatal tumors are rare, neuroblastoma is the most common neoplasia among them. These tumors, which usually involve children in early infancy, are derived from neural crest cells of adrenal gland medulla or sympathetic ganglia. Even though congenital metastatic neuroblastoma presents a favorable prognosis, it may lead to death if not recognized and treated early on. The authors report the case of a 2-month-old child who was born from in vitro fertilization, and whose diagnosis was made after birth. The form of presentation of this case as a metastatic disease concerning this age group is noteworthy.
尽管新生儿肿瘤很罕见，但神经母细胞瘤是其中最常见的肿瘤。这些肿瘤通常累及婴幼儿，起源于肾上腺髓质或交感神经节的神经嵴细胞。即使先天性转移性神经母细胞瘤预后良好，但如果不及早识别和治疗，也可能导致死亡。作者报告了一例通过体外受精出生的2个月大儿童病例，其诊断在出生后做出。该病例以转移性疾病形式在这个年龄组中出现的情况值得关注。
