Pyörälä K, Salonen J T, Valkonen T
Cardiology. 1985;72(1-2):35-51. doi: 10.1159/000173839.
A marked increase in the coronary heart disease (CHD) mortality of working-age men and women occurred in Finland from the 1950s until the 1960s. Around the year 1970, CHD mortality started to decline and this decline still continues. In the age group 35-64 years the average annual decline of CHD mortality in the 1970s was 1.8% for men and 3.4% for women. Limited data available on trends in CHD morbidity show that the decline in CHD mortality is accompanied by a decline in the incidence of non-fatal myocardial infarction. CHD mortality and incidence are higher in east Finland than in west Finland and this east-west difference has so far persisted during the declining trend. The decline in CHD mortality and incidence in the 1970s has been preceded and paralleled by changes into favourable direction in dietary fat consumption and population mean levels for serum cholesterol, prevalence of smoking among adult Finnish men, control of hypertension by antihypertensive drug therapy, and management of patients with symptomatic CHD. Both the changes in life-styles and CHD risk factor levels, as well as changes in the management of patients with CHD, appear to have been contributing to the decline in CHD mortality and incidence in Finland.
从20世纪50年代到60年代,芬兰劳动年龄男性和女性的冠心病(CHD)死亡率显著上升。大约在1970年,冠心病死亡率开始下降,并且这种下降仍在继续。在35 - 64岁年龄组中,20世纪70年代冠心病死亡率的年平均下降幅度男性为1.8%,女性为3.4%。关于冠心病发病率趋势的现有数据有限,表明冠心病死亡率的下降伴随着非致命性心肌梗死发病率的下降。芬兰东部的冠心病死亡率和发病率高于西部,到目前为止,这种东西方差异在下降趋势中一直持续。20世纪70年代冠心病死亡率和发病率的下降之前以及同时,在饮食脂肪消费、人群血清胆固醇平均水平、芬兰成年男性吸烟率、通过抗高血压药物治疗控制高血压以及对有症状冠心病患者的管理等方面都朝着有利方向发生了变化。生活方式和冠心病危险因素水平的变化以及冠心病患者管理的变化,似乎都对芬兰冠心病死亡率和发病率的下降起到了推动作用。