Stamler J
Cardiology. 1985;72(1-2):11-22. doi: 10.1159/000173836.
During the years 1940-1967, age-adjusted mortality rates from coronary heart disease (CHD) rose in the USA by 14.1% for all persons aged 35-74. This upward trend was recorded for white men, black men, and black women, but not for white women. From 1968 to 1981 (year of latest record), the trend in the preceding period was reversed, i.e., CHD death rates decreased steadily, at a rate averaging about 3% per year. This downward trend has involved all age-sex-color groups in the adult population and all regions of the country. It has encompassed both main categories of CHD, i.e., acute myocardial infarction (AMI) and chronic ischemic heart disease (CIHD), the former more prominently than the latter, especially among adults aged 35-64. The US decline in CHD mortality rates is greater-absolutely and relatively-than that of any other country. US death rates from stroke have also fallen markedly over these years, so that death rates from the major cardiovascular diseases (CVD) and all causes also fell substantially, with savings of hundreds of thousands of people from premature death since 1968. Responding to vigorous development in the USA over the last 25 years of public policy and strategy for the prevention and control of the coronary epidemic, tens of millions of Americans have made changes in eating habits resulting in lower population mean intake of total fat, saturated fat, cholesterol; increased intake of polyunsaturated fats; decreased mean levels of serum cholesterol and rates of hypercholesterolemia. Prevalence rates of cigarette smoking among adults have also decreased markedly. Tens of millions have taken up leisure time exercise. All these changes have occurred more among the more educated-affluent than among the less educated-affluent. Over the last decade the proportion of persons with hypertension whose hypertension was detected, treated, and controlled has risen from 10 to 15% to embrace a majority of hypertensives. It is a reasonable inference that these mass changes in life-styles and life-style-related major CHD risk factors have contributed importantly to the large sustained declines in CHD, CVD, and all causes death rates in the USA. Concordant with this inference are data sets indicating greater declines in CHD mortality among the more educated-affluent strata than among the general population (matched for age-sex-color), in keeping with the greater changes in life-styles among the more educated-affluent, e.g., as exemplified by findings for physicians.(ABSTRACT TRUNCATED AT 400 WORDS)
在1940年至1967年期间,美国35至74岁所有人经年龄调整后的冠心病(CHD)死亡率上升了14.1%。白人男性、黑人男性和黑人女性都出现了这种上升趋势,但白人女性没有。从1968年到1981年(最新记录年份),前一时期的趋势发生了逆转,即冠心病死亡率稳步下降,平均每年下降约3%。这种下降趋势涉及成年人口中的所有年龄-性别-肤色群体以及该国所有地区。它涵盖了冠心病的两个主要类别,即急性心肌梗死(AMI)和慢性缺血性心脏病(CIHD),前者比后者更为明显,尤其是在35至64岁的成年人中。美国冠心病死亡率的下降幅度——无论是绝对幅度还是相对幅度——都大于其他任何国家。这些年来,美国中风死亡率也显著下降,因此主要心血管疾病(CVD)和所有原因的死亡率也大幅下降,自1968年以来使数十万人免于过早死亡。响应美国在过去25年中大力发展的预防和控制冠心病流行的公共政策和战略,数千万美国人改变了饮食习惯,导致总体脂肪、饱和脂肪、胆固醇的人均摄入量降低;多不饱和脂肪的摄入量增加;血清胆固醇平均水平和高胆固醇血症发病率下降。成年人吸烟率也显著下降。数千万人开始进行休闲运动。所有这些变化在受教育程度较高、较为富裕的人群中比在受教育程度较低、较为富裕的人群中更为明显。在过去十年中,高血压患者中高血压被检测、治疗和控制的比例从10%上升到15%,涵盖了大多数高血压患者。合理的推断是,这些生活方式以及与生活方式相关的主要冠心病危险因素的大规模变化,对美国冠心病、心血管疾病和所有原因死亡率的持续大幅下降起到了重要作用。与这一推断一致的是,数据集表明,在受教育程度较高、较为富裕的阶层中,冠心病死亡率的下降幅度大于普通人群(按年龄-性别-肤色匹配),这与受教育程度较高、较为富裕的人群生活方式变化更大相符,例如医生的研究结果所示。(摘要截选至400字)