Monavari Seyed Hamid Reza, Hadifar Shima, Mostafaei Shayan, Miri Ali, Keshavarz Mohsen, Babaei Farhad, Moghoofei Mohsen
Department of Virology, Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Department of Mycobacteriology and Pulmonary Research, Pasteur Institute, Tehran, Iran.
J Glob Infect Dis. 2017 Apr-Jun;9(2):66-72. doi: 10.4103/0974-777X.205173.
Rotavirus is associated with increased risk for severe diarrhea in infants and young children worldwide. This systematic review and meta-analysis was performed to determine the prevalence rate of rotavirus from different parts of Iran and provide an overall relative frequency (RF) for Iran. We performed a systematic literature review from several databases including PubMed, ISI Web of Science, Scopus, OVID, MAG IRAN, IranMedex, and Iranian Scientific Information Database. We searched the following keywords: "rotavirus," "rotavirus infection," "acute gastroenteritis," "diarrhea," "children," "infant," and "Iran." The purpose of this study was to report the prevalence of rotavirus with the application of meta-analysis. We selected 43 researches out of 1147 for our study. From all the samples, the pooled estimate of prevalence (95% confidence interval) =39.9% (0.396%-0.409%) were rotavirus positive. It should be noted that rotavirus infection's RF varied from 6.4% to 79.3% in Birjand and Tehran Provinces, respectively. Thereupon, it is divergent in different studies. According to our study result, rotavirus RF has a wide range in Iran and is associated with diarrhea in children. Thus, further researches should be taken to minimize the emergence and transmission of rotavirus.
轮状病毒与全球婴幼儿严重腹泻风险增加有关。本系统评价和荟萃分析旨在确定伊朗不同地区轮状病毒的流行率，并提供伊朗的总体相对频率（RF）。我们对包括PubMed、ISI科学网、Scopus、OVID、MAG IRAN、IranMedex和伊朗科学信息数据库在内的多个数据库进行了系统文献回顾。我们搜索了以下关键词：“轮状病毒”、“轮状病毒感染”、“急性胃肠炎”、“腹泻”、“儿童”、“婴儿”和“伊朗”。本研究的目的是通过荟萃分析报告轮状病毒的流行率。我们从1147项研究中筛选出43项用于我们的研究。在所有样本中，轮状病毒阳性的合并患病率估计值（95%置信区间）=39.9%（0.396%-0.409%）。需要注意的是，比尔詹德省和德黑兰省轮状病毒感染的相对频率分别为6.4%至79.3%。因此，不同研究结果存在差异。根据我们的研究结果，伊朗轮状病毒的相对频率范围很广，且与儿童腹泻有关。因此，应进一步开展研究，以尽量减少轮状病毒的出现和传播。
