2012 - 2013年乌干达中部因急性腹泻住院的五岁以下儿童轮状病毒疾病流行病学
The epidemiology of rotavirus disease in under-five-year-old children hospitalized with acute diarrhea in central Uganda, 2012-2013.
作者信息
Bwogi Josephine, Malamba Samuel, Kigozi Brian, Namuwulya Prossy, Tushabe Phionah, Kiguli Sarah, Byarugaba Denis Karuhize, Desselberger Ulrich, Iturriza-Gomara Miren, Karamagi Charles
机构信息
Uganda Virus Research Institute, 51-59 Nakiwogo Road, P.O. BOX 49, Entebbe, Uganda.
Department of Paediatrics and Child Health, College of Health Sciences, Makerere University, P.O. BOX 7072, Kampala, Uganda.
出版信息
Arch Virol. 2016 Apr;161(4):999-1003. doi: 10.1007/s00705-015-2742-2. Epub 2016 Jan 2.
Abstract
A cross-sectional study was undertaken during 2012-2013 to determine the prevalence, strains and factors associated with rotavirus infection among under-5-year-old children hospitalized with acute diarrhea in Uganda. Rotaviruses were detected in 37 % (263/712) of the children. The most prevalent strains were G9P[8] (27 %, 55/204) and G12P[4] (18.6 %, 38/204). Mixed infections were detected in 22.5 % (46/204) of the children. The study suggests that consumption of raw vegetables (OR = 1.45, 95 % CI = 1.03-2.03) and family ownership of dogs (OR = 1.9, 95 % CI = 1.04-3.75) increases the risk of rotavirus infection. The study findings will be used to assess the impact of RV vaccination in Uganda.
摘要
2012年至2013年期间开展了一项横断面研究，以确定乌干达因急性腹泻住院的5岁以下儿童中轮状病毒感染的患病率、毒株及相关因素。在37%（263/712）的儿童中检测到轮状病毒。最常见的毒株是G9P[8]（27%，55/204）和G12P[4]（18.6%，38/204）。22.5%（46/204）的儿童检测到混合感染。该研究表明，食用生蔬菜（比值比=1.45，95%置信区间=1.03 - 2.03）和家庭养狗（比值比=1.9，95%置信区间=1.04 - 3.75）会增加轮状病毒感染风险。研究结果将用于评估乌干达轮状病毒疫苗接种的影响。
相似文献
1
The epidemiology of rotavirus disease in under-five-year-old children hospitalized with acute diarrhea in central Uganda, 2012-2013.2012 - 2013年乌干达中部因急性腹泻住院的五岁以下儿童轮状病毒疾病流行病学
Arch Virol. 2016 Apr;161(4):999-1003. doi: 10.1007/s00705-015-2742-2. Epub 2016 Jan 2.
2
Epidemiology of rotavirus A diarrhea in Chókwè, Southern Mozambique, from February to September, 2011.2011 年 2 月至 9 月，莫桑比克南部乔奎腹泻轮状病毒 A 的流行病学。
J Med Virol. 2016 Oct;88(10):1751-8. doi: 10.1002/jmv.24531. Epub 2016 Mar 29.
3
Prevalence and characterization of rotaviruses in children hospitalized for diarrheal disease in a tertiary care hospital, Pune.浦那一家三级护理医院中因腹泻病住院儿童的轮状病毒流行情况及特征分析
Indian J Med Microbiol. 2017 Jan-Mar;35(1):33-36. doi: 10.4103/ijmm.IJMM_16_94.
4
Molecular epidemiology of Rotavirus causing diarrhea among children less than five years of age visiting national level children hospitals, Nepal.尼泊尔国家级儿童医院五岁以下腹泻儿童中轮状病毒的分子流行病学研究
BMC Pediatr. 2017 Apr 7;17(1):101. doi: 10.1186/s12887-017-0858-0.
5
Predominance of rotavirus G2P[4] and emergence of G12P[9] strains in Asunción, Paraguay, 2006-2007.2006-2007 年在巴拉圭亚松森，轮状病毒 G2P[4]占主导地位和 G12P[9]株的出现。
Arch Virol. 2010 Apr;155(4):525-33. doi: 10.1007/s00705-010-0617-0. Epub 2010 Mar 7.
6
Prevalence and genetic diversity of rotavirus infection in children with acute gastroenteritis in a hospital setting, Nairobi Kenya in post vaccination era: a cross-sectional study.疫苗接种后时代肯尼亚内罗毕一家医院环境中急性胃肠炎患儿轮状病毒感染的患病率和基因多样性：一项横断面研究
Pan Afr Med J. 2017 Jan 24;26:38. doi: 10.11604/pamj.2017.26.38.10312. eCollection 2017.
7
Prevalence and factors associated with rotavirus infection among children admitted with acute diarrhea in Uganda.乌干达急性腹泻住院儿童轮状病毒感染的流行情况及相关因素分析。
BMC Pediatr. 2010 Sep 24;10:69. doi: 10.1186/1471-2431-10-69.
8
Molecular epidemiology of rotavirus and norovirus in Ile-Ife, Nigeria: high prevalence of G12P[8] rotavirus strains and detection of a rare norovirus genotype.尼日利亚伊费分子流行病学研究：轮状病毒和诺如病毒的流行情况：G12P[8]轮状病毒株高发率和罕见诺如病毒基因型的检出。
J Med Virol. 2012 Sep;84(9):1489-96. doi: 10.1002/jmv.23343.
9
Complete genotyping of unusual species A rotavirus G12P[11] and G10P[14] isolates and evidence of frequent in vivo reassortment among the rotaviruses detected in children with diarrhea in Kolkata, India, during 2014.2014年印度加尔各答腹泻儿童中检测到的A组轮状病毒G12P[11]和G10P[14]不寻常毒株的全基因分型以及轮状病毒频繁体内重配的证据
Arch Virol. 2016 Oct;161(10):2773-85. doi: 10.1007/s00705-016-2969-6. Epub 2016 Jul 22.
10
Increased frequency of rotavirus G3P[8] and G12P[8] in Argentina during 2008-2009: whole-genome characterization of emerging G12P[8] strains.2008-2009 年期间阿根廷轮状病毒 G3P[8]和 G12P[8]流行率增高：新兴 G12P[8] 株的全基因组特征。
J Clin Virol. 2012 Jun;54(2):162-7. doi: 10.1016/j.jcv.2012.02.011. Epub 2012 Mar 10.
引用本文的文献
1
Effectiveness of monovalent rotavirus vaccine against hospital-attended rotavirus gastroenteritis among children in Uganda.单价轮状病毒疫苗对乌干达儿童医院就诊的轮状病毒肠胃炎的有效性。
Vaccine. 2025 Feb 27;48:126726. doi: 10.1016/j.vaccine.2025.126726. Epub 2025 Jan 14.
2
Coverage and distributional benefit-cost of rotavirus vaccine in Uganda: an analysis of routine health facility aggregated data.乌干达轮状病毒疫苗的覆盖范围及分配效益成本：对常规卫生机构汇总数据的分析
Cost Eff Resour Alloc. 2024 Nov 22;22(1):85. doi: 10.1186/s12962-024-00586-5.
3
Genetic Profile of Rotavirus Type A in Children under 5 Years Old in Africa: A Systematic Review of Prevalence.非洲 5 岁以下儿童轮状病毒 A 型的基因谱：流行率的系统评价。
Viruses. 2024 Feb 3;16(2):243. doi: 10.3390/v16020243.
4
Analysing the interplay of environmental virology, public health, and sanitation: a comprehensive review from a Kenyan perspective.分析环境病毒学、公共卫生和卫生设施之间的相互作用：从肯尼亚角度进行的全面综述。
Front Cell Infect Microbiol. 2023 Oct 24;13:1256822. doi: 10.3389/fcimb.2023.1256822. eCollection 2023.
5
Co-Surveillance of Rotaviruses in Humans and Domestic Animals in Central Uganda Reveals Circulation of Wide Genotype Diversity in the Animals.乌干达中部开展的人兽轮状病毒共同监测揭示了动物中广泛的基因型多样性流行。
Viruses. 2023 Mar 13;15(3):738. doi: 10.3390/v15030738.
6
Prevalence and characteristics of rotavirus acute gastroenteritis among under-five children in ahmadu bello university teaching hospital, Zaria, Nigeria.尼日利亚扎里亚 Ahmadu Bello 大学教学医院 5 岁以下儿童轮状病毒急性胃肠炎的流行情况和特征。
Ann Afr Med. 2022 Jul-Sep;21(3):283-287. doi: 10.4103/aam.aam_31_21.
7
Prevalence of diarrhoea and associated risk factors among children under five years old in Pader District, northern Uganda.乌干达北部帕德尔区五岁以下儿童腹泻的流行情况及相关危险因素。
BMC Infect Dis. 2020 Jan 13;20(1):37. doi: 10.1186/s12879-020-4770-0.
8
Whole genome analysis of selected human and animal rotaviruses identified in Uganda from 2012 to 2014 reveals complex genome reassortment events between human, bovine, caprine and porcine strains.对2012年至2014年在乌干达发现的部分人类和动物轮状病毒进行的全基因组分析表明，人类、牛、山羊和猪的病毒株之间发生了复杂的基因组重配事件。
PLoS One. 2017 Jun 22;12(6):e0178855. doi: 10.1371/journal.pone.0178855. eCollection 2017.
9
Epidemiology of Rotavirus in the Iranian Children: A Systematic Review and Meta-analysis.伊朗儿童轮状病毒流行病学：系统评价与荟萃分析
J Glob Infect Dis. 2017 Apr-Jun;9(2):66-72. doi: 10.4103/0974-777X.205173.
本文引用的文献
1
Global, regional, and national causes of child mortality in 2000-13, with projections to inform post-2015 priorities: an updated systematic analysis.2000-13 年全球、区域和国家儿童死亡原因及其对 2015 年后重点的影响：更新系统分析。
Lancet. 2015 Jan 31;385(9966):430-40. doi: 10.1016/S0140-6736(14)61698-6. Epub 2014 Sep 30.
2
Decline in severe diarrhea hospitalizations after the introduction of rotavirus vaccination in Ghana: a prevalence study.加纳引入轮状病毒疫苗后严重腹泻住院率下降：一项患病率研究。
BMC Infect Dis. 2014 Aug 6;14:431. doi: 10.1186/1471-2334-14-431.
3
Rotavirus surveillance in Kisangani, the Democratic Republic of the Congo, reveals a high number of unusual genotypes and gene segments of animal origin in non-vaccinated symptomatic children.刚果民主共和国基桑加尼的轮状病毒监测显示，在未接种疫苗的有症状儿童中存在大量异常基因型和动物源基因片段。
PLoS One. 2014 Jun 26;9(6):e100953. doi: 10.1371/journal.pone.0100953. eCollection 2014.
4
Rotavirus prevalence and genotypes among children younger than 5 years with acute diarrhea at Mulago National Referral Hospital, Kampala, Uganda.乌干达坎帕拉穆拉戈国家转诊医院 5 岁以下急性腹泻儿童的轮状病毒流行率和基因型。
Pediatr Infect Dis J. 2014 Jan;33 Suppl 1:S41-4. doi: 10.1097/INF.0000000000000070.
5
Burden and aetiology of diarrhoeal disease in infants and young children in developing countries (the Global Enteric Multicenter Study, GEMS): a prospective, case-control study.发展中国家婴幼儿腹泻疾病负担和病因学（全球肠道发病和生存研究，GEMS）：一项前瞻性、病例对照研究。
Lancet. 2013 Jul 20;382(9888):209-22. doi: 10.1016/S0140-6736(13)60844-2. Epub 2013 May 14.
6
Modifiable diarrhoea risk factors in Egyptian children aged <5 years.埃及<5 岁儿童可改变的腹泻风险因素。
Epidemiol Infect. 2013 Dec;141(12):2547-59. doi: 10.1017/S0950268813000319. Epub 2013 Feb 22.
7
Ecological analysis of social risk factors for Rotavirus infections in Berlin, Germany, 2007-2009.2007-2009 年德国柏林轮状病毒感染的社会危险因素生态分析。
Int J Health Geogr. 2012 Aug 28;11:37. doi: 10.1186/1476-072X-11-37.
8
Prevalence and factors associated with Group A rotavirus infection among children with acute diarrhea in Mwanza, Tanzania.坦桑尼亚姆万扎急性腹泻儿童中A组轮状病毒感染的患病率及相关因素
J Infect Dev Ctries. 2012 Jun 15;6(6):508-15. doi: 10.3855/jidc.1816.
9
Seasonality of rotavirus in South Asia: a meta-analysis approach assessing associations with temperature, precipitation, and vegetation index.南亚轮状病毒的季节性：一项荟萃分析方法，评估与温度、降水和植被指数的关联。
PLoS One. 2012;7(5):e38168. doi: 10.1371/journal.pone.0038168. Epub 2012 May 31.
10
VP6-sequence-based cutoff values as a criterion for rotavirus species demarcation.基于 VP6 序列的截断值作为轮状病毒种间划分的标准。
Arch Virol. 2012 Jun;157(6):1177-82. doi: 10.1007/s00705-012-1273-3. Epub 2012 Mar 20.
Zotero 插件