Shrestha Sandeep, Chaudhary Nagendra, Koirala Sujit, Gupta Ruchi
Department of Pediatrics, Universal College of Medical Sciences, Bhairahawa 32900, Nepal.
Case Rep Pediatr. 2017;2017:4836142. doi: 10.1155/2017/4836142. Epub 2017 May 11.
Sclerema neonatorum is a form of panniculitides characterized by diffuse hardening of subcutaneous tissue with minimal inflammation. It usually affects ill and preterm neonates. Prognosis is usually poor in many cases despite aggressive management. Various treatment modalities (antibiotics, intravenous immunoglobulin, steroids, and exchange transfusion) have been explained in literature. Steroids due to its easy availability and low cost can prove to be lifesaving in such cases, especially in resource poor countries. Here, we report a case of sclerema neonatorum in a one-week preterm baby treated successfully with parenteral steroids and antibiotics.
新生儿硬化症是一种脂膜炎,其特征为皮下组织弥漫性硬化且炎症轻微。它通常影响患病的早产儿。尽管采取了积极的治疗措施,但在许多情况下预后通常较差。文献中已阐述了各种治疗方式(抗生素、静脉注射免疫球蛋白、类固醇和换血疗法)。类固醇因其易于获取且成本低廉,在这类病例中可能被证明是救命的,尤其是在资源匮乏的国家。在此,我们报告一例一周大的早产儿患新生儿硬化症,经胃肠外给予类固醇和抗生素成功治愈的病例。