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利用有机纳米材料的近红外光触发药物传递的新兴策略。

Emerging strategies in near-infrared light triggered drug delivery using organic nanomaterials.

机构信息

Department of Chemical Engineering, Virginia Polytechnic Institute and State University, 635 Prices Fork Road, Blacksburg, Virginia 24061, USA.

出版信息

Biomater Sci. 2017 Jul 25;5(8):1491-1499. doi: 10.1039/c7bm00348j.

DOI:10.1039/c7bm00348j
PMID:28589987
Abstract

Near-infrared light has significant advantages for light-triggered drug delivery systems within deep tissues. The use of inorganic nanomaterials raises concern over their long-term in vivo toxicities. Here we will highlight emerging near-infrared light-triggered drug delivery using organic nanomaterials, as well as new photocleavage reactions mediated by near-infrared light.

摘要

近红外光在深层组织内的光触发药物输送系统中具有显著优势。无机纳米材料的使用引起了人们对其长期体内毒性的关注。在这里,我们将重点介绍新兴的近红外光触发的有机纳米材料药物输送系统,以及近红外光介导的新的光解反应。

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