Ford T F, Parkinson M C, Pryor J P
Br J Urol. 1985 Apr;57(2):181-4. doi: 10.1111/j.1464-410x.1985.tb06417.x.
The management of the undescended testis in the adult patient presents problems in terms of locating the impalpable gonad, the risk of malignancy and prognosis with regard to fertility. CT scanning has been used to locate four intra-abdominal testes. The risk of malignancy has been assessed by determining the incidence of carcinoma in situ after orchiectomy or testicular biopsy in 90 patients (112 testes). Carcinoma in situ was found in 4 of 16 abdominal, 3 of 44 inguinal and none of 52 scrotal testes following orchiopexy in childhood. Seventy per cent of undescended testes in adult patients had no evidence of spermatogenesis. This fact, together with the risk of malignancy in those testes in which germ cells are present, suggests that orchiectomy should be performed in unilateral cases. Testicular biopsy is essential if an undescended testis is to be preserved for androgenic function.
成年患者隐睾的管理在难以触及性腺的定位、恶性肿瘤风险以及生育预后方面存在问题。CT扫描已被用于定位4个腹腔内睾丸。通过确定90例患者(112个睾丸)在睾丸切除或睾丸活检后原位癌的发生率来评估恶性肿瘤风险。在儿童期睾丸固定术后,16个腹腔内睾丸中有4个发现原位癌,44个腹股沟睾丸中有3个发现原位癌,52个阴囊内睾丸中未发现原位癌。成年患者中70%的隐睾无精子发生证据。这一事实,连同那些存在生殖细胞的睾丸的恶性肿瘤风险,表明单侧病例应行睾丸切除术。如果要保留隐睾以维持雄激素功能,睾丸活检至关重要。