Liu Qing-Guang, Liu Lin, Huang Qiang-Min, Nguyen Thi-Tham, Ma Yan-Tao, Zhao Jia-Min
Department of Sport Rehabilitation, School of Kinesiology, Shanghai University of Sport, Shanghai, China.
Evid Based Complement Alternat Med. 2017;2017:3938191. doi: 10.1155/2017/3938191. Epub 2017 May 16.
The aims of this study are to investigate the changes in spontaneous electrical activities (SEAs) and in acetylcholine (ACh), acetylcholine receptor (AChR), and acetylcholine esterase (AChE) levels after dry needling at myofascial trigger spots in model rats.
Forty-eight male Sprague-Dawley rats were divided into four groups. Thirty-six rats were assigned to three model groups, which underwent MTrSs modeling intervention. Twelve rats were assigned to the blank control (BC) group. After model construction, the 36 model rats were randomly subdivided into three groups according to treatment: MTrSs model control (MC) and two dry needling groups. One dry needling group received puncturing at MTrSs (DN-M), whereas the other underwent puncturing at non-MTrSs (DN-nM). Dry needling treatment will last for two weeks, once a week. SEAs and ACh, AChR, and AChE levels were measured after one-week rest of dry needling treatment.
The amplitudes and frequencies of endplate noise (EPN) and endplate spike (EPS) significantly decreased after dry needling treatment in the DN-M group. Moreover, ACh and AChR levels significantly decreased, whereas AChE significantly increased after dry needling treatment in the DN-M group.
Dry needling at the exact MTrSs is more effective than dry needling at non-MTrSs.
本研究旨在探讨模型大鼠肌筋膜触发点干针治疗后自发电活动（SEAs）以及乙酰胆碱（ACh）、乙酰胆碱受体（AChR）和乙酰胆碱酯酶（AChE）水平的变化。
48只雄性Sprague-Dawley大鼠分为四组。36只大鼠被分配到三个模型组，接受肌筋膜触发点（MTrSs）建模干预。12只大鼠被分配到空白对照组（BC）。模型构建后，36只模型大鼠根据治疗方法随机分为三组：MTrSs模型对照组（MC）和两个干针组。一个干针组在MTrSs处进行针刺（DN-M），而另一个在非MTrSs处进行针刺（DN-nM）。干针治疗持续两周，每周一次。在干针治疗休息一周后测量SEAs以及ACh、AChR和AChE水平。
DN-M组干针治疗后终板噪声（EPN）和终板棘波（EPS）的幅度和频率显著降低。此外，DN-M组干针治疗后ACh和AChR水平显著降低，而AChE显著升高。
在准确的MTrSs处进行干针治疗比在非MTrSs处进行干针治疗更有效。
