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[孕期母体微生物群的重要性]

[The importance of maternal microbiome in pregnancy].

作者信息

Záhumenský J, Hederlingová J, Pšenková P

出版信息

Ceska Gynekol. 2017 Summer;82(3):211-217.

PMID:28593775
Abstract

OBJECTIVE

To bring the most actual published findings of the influence of maternal microbiome on the development of pregnancy and possibilities of its adjusting.

DESIGN

Review.

SETTING

2nd Department of Gyneacology and Obstetrics of the Faculty of Medicine and the University Hospital, Bratislava.

METHODS

Review of the literature.

CONCLUSIONS

The appearance of microbes on various body surface areas determines the overall health status of the individual in significant manner. The change in composition of microbioma in pregnant woman is well known. It was believed that the placenta and the body of the newborn is sterile environment. Modern diagnostic methods proved the presence of microorganisms inside the fetoplacentar unit without the signs of inflammation. Mutual interaction between the immune system of the mother, microbioma and immune system of the newborn can decrease the risk of serious obstetrical syndromes as well as define the lifelong health status of the newborn. The risk can be decreased by the administration of probiotics during the pregnancy.

摘要

目的

呈现关于母体微生物群对妊娠发展影响及其调节可能性的最实际已发表研究结果。

设计

综述。

地点

布拉迪斯拉发医学院和大学医院妇产科第二科室。

方法

文献综述。

结论

微生物在身体不同体表区域的出现以重要方式决定个体的整体健康状况。孕妇微生物群组成的变化是众所周知的。过去认为胎盘和新生儿体内是无菌环境。现代诊断方法证明胎儿 - 胎盘单位内存在微生物且无炎症迹象。母亲的免疫系统、微生物群与新生儿免疫系统之间的相互作用可降低严重产科综合征的风险,并确定新生儿的终身健康状况。孕期服用益生菌可降低这种风险。

相似文献

1
[The importance of maternal microbiome in pregnancy].[孕期母体微生物群的重要性]
Ceska Gynekol. 2017 Summer;82(3):211-217.
2
Review: Maternal health and the placental microbiome.综述:孕产妇健康与胎盘微生物组
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引用本文的文献

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Microbiota Dysbiosis: A Key Modulator in Preeclampsia Pathogenesis and Its Therapeutic Potential.微生物群失调:子痫前期发病机制中的关键调节因子及其治疗潜力
Microorganisms. 2025 Jan 23;13(2):245. doi: 10.3390/microorganisms13020245.
2
Is there a placental microbiota? A critical review and re-analysis of published placental microbiota datasets.胎盘是否存在微生物菌群?对已发表的胎盘微生物菌群数据集的批判性回顾和再分析。
BMC Microbiol. 2023 Mar 18;23(1):76. doi: 10.1186/s12866-023-02764-6.
3
Through the Microbial Looking Glass: Premature Labor, Preeclampsia, and Gestational Diabetes: A Scoping Review.
透过微生物的视角:早产、子痫前期和妊娠期糖尿病:一项范围综述
J Perinat Neonatal Nurs. 2019 Jan/Mar;33(1):35-51. doi: 10.1097/JPN.0000000000000375.