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球孢子菌病:一种报告不足的死因——亚利桑那州,2008 - 2013年

Coccidioidomycosis: An underreported cause of death-Arizona, 2008-2013.

作者信息

Jones Jefferson M, Koski Lia, Khan Mohammed, Brady Shane, Sunenshine Rebecca, Komatsu Ken K

机构信息

Centers for Disease Control and Prevention, Atlanta, Georgia, USA; Maricopa County Department of Public Health, Phoenix, Arizona, USA; and Arizona Department of Health Services, Phoenix, Arizona, USA.

Maricopa County Department of Public Health, Phoenix, Arizona, USA.

出版信息

Med Mycol. 2018 Feb 1;56(2):172-179. doi: 10.1093/mmy/myx041.

Abstract

In Arizona during 1997-2013, coccidioidomycosis increased from 21 to 90 cases/100,000 population, but coccidioidomycosis-associated deaths remained stable at 3-6 deaths/million population. We used the capture-recapture method by using death certificates and hospital discharge data to more fully estimate the total number of coccidioidomycosis-attributable deaths and compared this with published estimates. Death certificates were included if any cause of death included coccidioidomycosis; hospital discharge data deaths were included if any discharge diagnosis included coccidioidomycosis and laboratory confirmation. Among deaths during 2008-2013, we identified 529 coccidioidomycosis-attributable deaths from death certificates and 560 from hospital discharge data, with 251 deaths identified in both databases. Capture-recapture estimated 1,178 total coccidioidomycosis-attributable deaths, compared with 164 deaths (underlying cause of death) or 529 deaths (any cause of death) on death certificates. Coccidioidomycosis-attributable deaths are underreported from two- to sevenfold on Arizona death certificates, demonstrating an education need for death certifiers to document coccidioidomycosis mortality.

摘要

在1997 - 2013年期间的亚利桑那州,球孢子菌病的发病率从每10万人21例增至90例,但球孢子菌病相关的死亡人数保持稳定,为每百万人口3 - 6例死亡。我们采用捕获 - 再捕获法,利用死亡证明和医院出院数据来更全面地估计球孢子菌病所致死亡的总数,并将其与已发表的估计数进行比较。如果死亡原因中包含球孢子菌病,则纳入死亡证明;如果出院诊断中包含球孢子菌病且有实验室确诊,则纳入医院出院数据中的死亡病例。在2008 - 2013年期间的死亡病例中,我们从死亡证明中确定了529例球孢子菌病所致死亡,从医院出院数据中确定了560例,两个数据库中均确定的死亡病例有251例。捕获 - 再捕获法估计球孢子菌病所致死亡总数为1178例,而死亡证明上显示的(死亡根本原因)为164例死亡或(任何死亡原因)为529例死亡。亚利桑那州死亡证明上球孢子菌病所致死亡的漏报率达2至7倍,这表明有必要对死亡证明开具人员进行教育,使其记录球孢子菌病死亡率。

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