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精神分裂症的反应时间、处理速度和持续注意力:对社会功能的影响。

Reaction time, processing speed and sustained attention in schizophrenia: impact on social functioning.

机构信息

Universidad de Alcalá, Instituto Ramón y Cajal de Investigación Sanitaria, CIBERSAM, Madrid, España.

Hospital Universitario Príncipe de Asturias, Alcalá de Henares, Madrid, España.

出版信息

Rev Psiquiatr Salud Ment. 2017 Oct-Dec;10(4):197-205. doi: 10.1016/j.rpsm.2017.04.001. Epub 2017 Jun 7.

DOI:10.1016/j.rpsm.2017.04.001
PMID:28596126
Abstract

INTRODUCTION

Previous studies have linked processing speed with social cognition and functioning of patients with schizophrenia. A discriminant analysis is needed to determine the different components of this neuropsychological construct. This paper analyzes the impact of processing speed, reaction time and sustained attention on social functioning.

MATERIAL AND METHODS

98 outpatients between 18 and 65 with DSM-5 diagnosis of schizophrenia, with a period of 3 months of clinical stability, were recruited. Sociodemographic and clinical data were collected, and the following variables were measured: processing speed (Trail Making Test [TMT], symbol coding [BACS], verbal fluency), simple and elective reaction time, sustained attention, recognition of facial emotions and global functioning.

RESULTS

Processing speed (measured only through the BACS), sustained attention (CPT) and elective reaction time (but not simple) were associated with functioning. Recognizing facial emotions (FEIT) correlated significantly with scores on measures of processing speed (BACS, Animals, TMT), sustained attention (CPT) and reaction time. The linear regression model showed a significant relationship between functioning, emotion recognition (P=.015) and processing speed (P=.029).

CONCLUSIONS

A deficit in processing speed and facial emotion recognition are associated with worse global functioning in patients with schizophrenia.

摘要

简介

先前的研究将加工速度与精神分裂症患者的社会认知和功能联系起来。需要进行判别分析以确定该神经心理学结构的不同组成部分。本文分析了加工速度、反应时和持续注意力对社会功能的影响。

材料与方法

招募了 98 名年龄在 18 至 65 岁之间、符合 DSM-5 精神分裂症诊断标准、临床稳定期为 3 个月的门诊患者。收集了人口统计学和临床数据,并测量了以下变量:加工速度(连线测试[TMT]、符号编码[BACS]、词语流畅性)、简单和选择性反应时、持续注意力、面部情绪识别和整体功能。

结果

加工速度(仅通过 BACS 测量)、持续注意力(CPT)和选择性反应时(而非简单反应时)与功能相关。面部情绪识别(FEIT)与加工速度(BACS、动物、TMT)、持续注意力(CPT)和反应时的测量分数显著相关。线性回归模型显示,功能、情绪识别(P=.015)和加工速度(P=.029)之间存在显著关系。

结论

加工速度和面部情绪识别缺陷与精神分裂症患者的整体功能较差相关。

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