• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

微流控芯片上精确液滴控制的热毛细力估算及其应用。

Estimation of the thermocapillary force and its applications to precise droplet control on a microfluidic chip.

机构信息

Dept. of Mechanical Engineering, Hanyang University, Seoul, 04763, Korea.

Insitute of Nano Science and Technology, Hanyang University, Seoul, 04763, Korea.

出版信息

Sci Rep. 2017 Jun 8;7(1):3062. doi: 10.1038/s41598-017-03028-w.

DOI:10.1038/s41598-017-03028-w
PMID:28596574
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5465069/
Abstract

Droplet control through the use of light-induced thermocapillary effects has recently garnered attention due to its non-intrusive and multifunctional nature. An important issue in droplet control is the estimation of the thermocapillary force. The purpose of the present study is to estimate the thermocapillary force and propose empirical equations between the force and simply measurable key parameters such as droplet diameter and power of heat source. In addition, we aim to shift the droplet trajectory and develop an on-demand droplet routing system based on the estimation of the thermocapillary force. We illuminated a continuous phase with a 532 nm laser beam to minimize possible damage or property changes to target molecules contained within droplets. A mixture of light-absorbing material and oleic acid was used for the continuous phase fluid, while deionized water (DI water) was used for the dispersed phase fluid. We proposed empirical equations to estimate the thermocapillary force, which was then applied to precise droplet shifting and routing. We found that the shifting distance was linearly proportional to the thermocapillary force, and that an on-demand droplet routing system resulted in a success rate greater than 95%.

摘要

由于光致热毛细效应的非侵入性和多功能性,通过该效应控制液滴最近受到了关注。在液滴控制中,一个重要的问题是热毛细力的估计。本研究的目的是估计热毛细力,并提出力与简单可测量的关键参数(如液滴直径和热源功率)之间的经验方程。此外,我们旨在根据热毛细力的估计来改变液滴轨迹并开发按需液滴路由系统。我们用 532nm 激光束照射连续相,以最小化可能对液滴中包含的目标分子造成的损害或性质变化。连续相流体使用了光吸收材料和油酸的混合物,而分散相流体则使用去离子水(DI 水)。我们提出了经验方程来估计热毛细力,然后将其应用于精确的液滴移动和路由。我们发现,移动距离与热毛细力成正比,并且按需液滴路由系统的成功率大于 95%。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1990/5465069/8a5c8cbfc32e/41598_2017_3028_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1990/5465069/cb8acc06a16c/41598_2017_3028_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1990/5465069/939389c610e8/41598_2017_3028_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1990/5465069/87ce214ed4eb/41598_2017_3028_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1990/5465069/94bf51b7a2cb/41598_2017_3028_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1990/5465069/8a5c8cbfc32e/41598_2017_3028_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1990/5465069/cb8acc06a16c/41598_2017_3028_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1990/5465069/939389c610e8/41598_2017_3028_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1990/5465069/87ce214ed4eb/41598_2017_3028_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1990/5465069/94bf51b7a2cb/41598_2017_3028_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1990/5465069/8a5c8cbfc32e/41598_2017_3028_Fig5_HTML.jpg

相似文献

1
Estimation of the thermocapillary force and its applications to precise droplet control on a microfluidic chip.微流控芯片上精确液滴控制的热毛细力估算及其应用。
Sci Rep. 2017 Jun 8;7(1):3062. doi: 10.1038/s41598-017-03028-w.
2
Thermocapillary migration in small-scale temperature gradients: application to optofluidic drop dispensing.小尺度温度梯度下的热毛细迁移:在光流体液滴分配中的应用
Phys Rev E Stat Nonlin Soft Matter Phys. 2012 Feb;85(2 Pt 2):026310. doi: 10.1103/PhysRevE.85.026310. Epub 2012 Feb 10.
3
Generation and manipulation of oil-in-water micro-droplets by confined thermocapillary microvortices.受限热毛细微涡旋生成和操控水包油型微液滴。
Opt Lett. 2020 Apr 1;45(7):1998-2001. doi: 10.1364/OL.388188.
4
Acoustothermal tweezer for droplet sorting in a disposable microfluidic chip.用于在一次性微流控芯片中对液滴进行分类的声热镊子。
Lab Chip. 2017 Mar 14;17(6):1031-1040. doi: 10.1039/c6lc01405d.
5
Dual-mode on-demand droplet routing in multiple microchannels using a magnetic fluid as carrier phase.使用磁流体作为载体相在多个微通道中进行双模式按需液滴路由。
Biomicrofluidics. 2014 Sep 8;8(5):054105. doi: 10.1063/1.4894748. eCollection 2014 Sep.
6
Ultrasonic surface acoustic wave-assisted separation of microscale droplets with varying acoustic impedance.超声表面声波辅助分离具有不同声阻抗的微尺度液滴。
Ultrason Sonochem. 2023 Feb;93:106305. doi: 10.1016/j.ultsonch.2023.106305. Epub 2023 Jan 18.
7
A Noncontact Picolitor Droplet Handling by Photothermal Control of Interfacial Flow.通过界面流的光热控制实现非接触式皮升液滴处理。
Anal Sci. 2016;32(1):49-55. doi: 10.2116/analsci.32.49.
8
Thermocapillary valve for droplet production and sorting.用于液滴产生和分选的热毛细阀。
Phys Rev E Stat Nonlin Soft Matter Phys. 2007 Apr;75(4 Pt 2):046302. doi: 10.1103/PhysRevE.75.046302. Epub 2007 Apr 5.
9
Demand-driven active droplet generation and sorting based on positive pressure-controlled fluid wall.基于正压控制流体壁的需求驱动主动液滴生成与分选
Anal Bioanal Chem. 2023 Sep;415(22):5311-5322. doi: 10.1007/s00216-023-04806-4. Epub 2023 Jul 1.
10
Planar digital nanoliter dispensing system based on thermocapillary actuation.基于热毛细作用的平面数字纳升分配系统。
Lab Chip. 2010 Apr 21;10(8):1061-71. doi: 10.1039/b921759b. Epub 2010 Feb 3.

引用本文的文献

1
Optimizing Optical Dielectrophoretic (ODEP) Performance: Position- and Size-Dependent Droplet Manipulation in an Open-Chamber Oil Medium.优化光学介电泳(ODEP)性能:在开放式腔室油介质中基于位置和尺寸的液滴操控
Micromachines (Basel). 2024 Jan 11;15(1):119. doi: 10.3390/mi15010119.
2
Generation of Fermat's spiral patterns by solutal Marangoni-driven coiling in an aqueous two-phase system.在水两相系统中通过溶质马兰戈尼驱动的盘绕生成费马螺旋图案。
Nat Commun. 2022 Nov 23;13(1):7206. doi: 10.1038/s41467-022-34368-5.
3
Merging microfluidics with luminescence immunoassays for urgent point-of-care diagnostics of COVID-19.

本文引用的文献

1
Marangoni effect visualized in two-dimensions Optical tweezers for gas bubbles.在二维光学镊子中可视化马里兰效应用于气体气泡。
Sci Rep. 2016 Oct 7;6:34787. doi: 10.1038/srep34787.
2
A Noncontact Picolitor Droplet Handling by Photothermal Control of Interfacial Flow.通过界面流的光热控制实现非接触式皮升液滴处理。
Anal Sci. 2016;32(1):49-55. doi: 10.2116/analsci.32.49.
3
Dynamic Magnetic Responsive Wall Array with Droplet Shedding-off Properties.具有液滴脱落特性的动态磁响应壁阵列
将微流控技术与发光免疫测定相结合用于新型冠状病毒病(COVID-19)的即时紧急床旁诊断。
Trends Analyt Chem. 2022 Dec;157:116814. doi: 10.1016/j.trac.2022.116814. Epub 2022 Nov 7.
4
A versatile interferometric technique for probing the thermophysical properties of complex fluids.一种用于探测复杂流体热物理性质的多功能干涉测量技术。
Light Sci Appl. 2022 Apr 28;11(1):115. doi: 10.1038/s41377-022-00796-7.
5
Heat-Mediated Optical Manipulation.热介导光学操控。
Chem Rev. 2022 Feb 9;122(3):3122-3179. doi: 10.1021/acs.chemrev.1c00626. Epub 2021 Nov 19.
6
Photopyroelectric microfluidics.光热释电微流体学
Sci Adv. 2020 Sep 16;6(38). doi: 10.1126/sciadv.abc1693. Print 2020 Sep.
7
Non-Newtonian droplet-based microfluidics logic gates.基于非牛顿液滴的微流控逻辑门。
Sci Rep. 2020 Jun 9;10(1):9293. doi: 10.1038/s41598-020-66337-7.
8
Micropatterning of Metal Nanoparticle Ink by Laser-Induced Thermocapillary Flow.通过激光诱导热毛细流对金属纳米颗粒墨水进行微图案化处理。
Nanomaterials (Basel). 2018 Aug 22;8(9):645. doi: 10.3390/nano8090645.
9
Stable Hydrothermal Waves at Steady State Evaporating Droplet Surface.稳态蒸发液滴表面的稳定热液波
Sci Rep. 2017 Nov 24;7(1):16219. doi: 10.1038/s41598-017-16582-0.
Sci Rep. 2015 Jun 10;5:11209. doi: 10.1038/srep11209.
4
Dual-mode on-demand droplet routing in multiple microchannels using a magnetic fluid as carrier phase.使用磁流体作为载体相在多个微通道中进行双模式按需液滴路由。
Biomicrofluidics. 2014 Sep 8;8(5):054105. doi: 10.1063/1.4894748. eCollection 2014 Sep.
5
Drops on soft surfaces learn the hard way.落在柔软表面上的液滴会有惨痛教训。
Proc Natl Acad Sci U S A. 2013 Jul 30;110(31):12505-6. doi: 10.1073/pnas.1310672110. Epub 2013 Jul 19.
6
Photo-actuation of liquids for light-driven microfluidics: state of the art and perspectives.光驱动微流控中的液体光致动:现状与展望。
Lab Chip. 2012 Oct 7;12(19):3637-53. doi: 10.1039/c2lc40596b.
7
Synthesis of monodispersed microspheres from laplace pressure induced droplets in micromolds.利用微模具中拉普拉斯压力诱导液滴合成单分散微球。
Adv Mater. 2012 Sep 25;24(37):5078-82, 5077. doi: 10.1002/adma.201200843. Epub 2012 Jul 16.
8
A unified platform for optoelectrowetting and optoelectronic tweezers.用于光电润湿和光电镊子的统一平台。
Lab Chip. 2011 Apr 7;11(7):1292-7. doi: 10.1039/c0lc00568a. Epub 2011 Feb 11.
9
A light-induced dielectrophoretic droplet manipulation platform.一种光诱导介电泳液滴操控平台。
Lab Chip. 2009 Nov 21;9(22):3228-35. doi: 10.1039/b909158k. Epub 2009 Sep 10.
10
Movement of micrometer-sized particles in the evanescent field of a laser beam.微米级粒子在激光束倏逝场中的运动。
Opt Lett. 1992 Jun 1;17(11):772-4. doi: 10.1364/ol.17.000772.