Flynn Harry W, Relhan Nidhi
Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami, Miller School of Medicine, Miami, Florida.
Ophthalmol Retina. 2017 Jan-Feb;1(1):3-7. doi: 10.1016/j.oret.2016.09.006.
To present the management options for vitreomacular traction (VMT) and to recommend an individualized approach to treatment selection.
Presented at the American Academy of Ophthalmology Annual Meeting, 2016, Chicago, October 15, 2016 (The Charles Schepens Lecture).
None.
Review of published literature and clinical trials.
Visual and anatomic outcomes of various treatment options for VMT were reviewed.
The management options for VMT include pars plana vitrectomy, pneumatic vitreolysis, enzymatic vitreolysis, and observation. The surgical management using pars plana vitrectomy offers the most effective approach for VMT, but there are inherent risks and cost issues. Pneumatic vitreolysis is reported to be cost-effective and may be an anatomically successful nonsurgical option for management. Enzymatic vitreolysis with intravitreal ocriplasmin is another nonsurgical option, but both short- and long-term side effects may occur. Observation in selected patients can be associated with stable visual outcomes during long-term follow-up.
The final management decision should be individualized for specific patients depending on the patient's clinical findings, potential risks, probable benefits, and costs of each option.
介绍玻璃体黄斑牵拉(VMT)的治疗选择,并推荐一种个体化的治疗选择方法。
2016年10月15日在芝加哥举行的美国眼科学会年会上发表(查尔斯·谢彭斯讲座)。
无。
回顾已发表的文献和临床试验。
回顾VMT各种治疗选择的视觉和解剖学结果。
VMT的治疗选择包括玻璃体切除术、气体消融术、酶解消融术和观察。采用玻璃体切除术的手术治疗为VMT提供了最有效的方法,但存在内在风险和成本问题。据报道,气体消融术具有成本效益,可能是一种解剖学上成功的非手术治疗选择。玻璃体内注射奥克纤溶酶进行酶解消融术是另一种非手术选择,但可能会出现短期和长期副作用。对部分患者进行观察在长期随访中可能与稳定的视觉结果相关。
最终的治疗决策应根据患者的临床发现、潜在风险、可能的益处以及每种选择的成本,为特定患者进行个体化制定。