University of Malaya Centre for Ionic Liquids (UMCiL), Department of Chemical Engineering, University of Malaya, Kuala Lumpur 50603, Malaysia.
University of Malaya Centre for Ionic Liquids (UMCiL), Department of Chemical Engineering, University of Malaya, Kuala Lumpur 50603, Malaysia; Institute of Halal Research University of Malaya (IHRUM), Academy of Islamic Studies, University of Malaya, Kuala Lumpur 50603, Malaysia.
Anal Chim Acta. 2017 Aug 1;979:1-23. doi: 10.1016/j.aca.2017.05.012. Epub 2017 May 26.
With the rapid development of ionic liquid analogues, termed 'deep eutectic solvents' (DESs), and their application in a wide range of chemical and biochemical processes in the past decade, the extraction of bioactive compounds has attracted significant interest. Recently, numerous studies have explored the extraction of bioactive compounds using DESs from diverse groups of natural sources, including animal and plant sources. This review summarizes the-state-of-the-art effort dedicated to the application of DESs in the extraction of bioactive compounds. The aim of this review also was to introduce conventional and recently-developed extraction techniques, with emphasis on the use of DESs as potential extractants for various bioactive compounds, such as phenolic acid, flavonoids, tanshinone, keratin, tocols, terpenoids, carrageenans, xanthones, isoflavones, α-mangostin, genistin, apigenin, and others. In the near future, DESs are expected to be used extensively for the extraction of bioactive compounds from various sources.
随着离子液体类似物（称为“深共晶溶剂”（DESs））的快速发展及其在过去十年中在广泛的化学和生化过程中的应用，对生物活性化合物的提取引起了极大的关注。最近，许多研究都探讨了从包括动物和植物来源在内的不同天然来源的 DESs 中提取生物活性化合物。这篇综述总结了致力于将 DESs 应用于生物活性化合物提取的最新研究进展。本综述的目的还在于介绍传统和最近开发的提取技术，重点介绍了 DESs 作为各种生物活性化合物（如酚酸、类黄酮、丹参酮、角蛋白、生育酚、萜类、卡拉胶、黄烷酮、异黄酮、α-倒捻子素、染料木素、芹菜素等）的潜在提取剂的应用。在不久的将来，预计 DESs 将广泛用于从各种来源提取生物活性化合物。
