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Increased Trimethylamine-N-Oxide (TMAO) Levels After Roux-en Y Gastric Bypass Surgery-Should We Worry About It?

作者信息

Schultes Bernd

机构信息

eSwiss Medical & Surgical Center, Brauerstrasse 97, CH-9016, St. Gallen, Switzerland.

出版信息

Obes Surg. 2017 Aug;27(8):2170-2173. doi: 10.1007/s11695-017-2757-8.

DOI:10.1007/s11695-017-2757-8
PMID:28601986
Abstract
摘要

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引用本文的文献

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J Gastrointest Surg. 2020 Aug;24(8):1736-1746. doi: 10.1007/s11605-019-04321-x. Epub 2019 Aug 6.

本文引用的文献

1
An Untargeted Metabolomics Approach to Characterize Short-Term and Long-Term Metabolic Changes after Bariatric Surgery.一种用于表征减肥手术后短期和长期代谢变化的非靶向代谢组学方法。
PLoS One. 2016 Sep 1;11(9):e0161425. doi: 10.1371/journal.pone.0161425. eCollection 2016.
2
Alterations of Gut Microbiota After Roux-en-Y Gastric Bypass and Sleeve Gastrectomy in Sprague-Dawley Rats.Roux-en-Y胃旁路术和袖状胃切除术对Sprague-Dawley大鼠肠道微生物群的影响
Obes Surg. 2017 Feb;27(2):295-302. doi: 10.1007/s11695-016-2297-7.
3
Intestinal Microbiota-Generated Metabolite Trimethylamine-N-Oxide and 5-Year Mortality Risk in Stable Coronary Artery Disease: The Contributory Role of Intestinal Microbiota in a COURAGE-Like Patient Cohort.
肠道微生物群产生的代谢物氧化三甲胺与稳定型冠状动脉疾病的5年死亡风险：肠道微生物群在类似COURAGE研究患者队列中的作用
J Am Heart Assoc. 2016 Jun 10;5(6):e002816. doi: 10.1161/JAHA.115.002816.
4
Plasma Trimethylamine N-Oxide, a Gut Microbe-Generated Phosphatidylcholine Metabolite, Is Associated With Atherosclerotic Burden.血浆三甲胺 N-氧化物，一种肠道微生物产生的磷脂酰胆碱代谢产物，与动脉粥样硬化负担相关。
J Am Coll Cardiol. 2016 Jun 7;67(22):2620-8. doi: 10.1016/j.jacc.2016.03.546.
5
Major Increase in Microbiota-Dependent Proatherogenic Metabolite TMAO One Year After Bariatric Surgery.减肥手术后一年，微生物群依赖的促动脉粥样硬化代谢物氧化三甲胺大幅增加。
Metab Syndr Relat Disord. 2016 May;14(4):197-201. doi: 10.1089/met.2015.0120. Epub 2016 Jan 26.
6
Trimethylamine N-Oxide Promotes Vascular Inflammation Through Signaling of Mitogen-Activated Protein Kinase and Nuclear Factor-κB.氧化三甲胺通过丝裂原活化蛋白激酶和核因子-κB信号传导促进血管炎症
J Am Heart Assoc. 2016 Feb 22;5(2):e002767. doi: 10.1161/JAHA.115.002767.
7
Metabolomic fingerprint of severe obesity is dynamically affected by bariatric surgery in a procedure-dependent manner.严重肥胖的代谢组指纹图谱以依赖于手术程序的方式动态地受到减重手术的影响。
Am J Clin Nutr. 2015 Dec;102(6):1313-22. doi: 10.3945/ajcn.115.110536. Epub 2015 Nov 18.
8
Cardiovascular disease and mortality in patients with type 2 diabetes after bariatric surgery in Sweden: a nationwide, matched, observational cohort study.瑞典 2 型糖尿病患者接受减重手术后的心血管疾病和死亡率：一项全国性、匹配的观察性队列研究。
Lancet Diabetes Endocrinol. 2015 Nov;3(11):847-54. doi: 10.1016/S2213-8587(15)00334-4. Epub 2015 Sep 28.
9
Effects of bariatric surgery on markers of subclinical atherosclerosis and endothelial function: a meta-analysis of literature studies.减肥手术对亚临床动脉粥样硬化标志物和内皮功能的影响：文献研究的荟萃分析
Int J Obes (Lond). 2016 Mar;40(3):395-402. doi: 10.1038/ijo.2015.187. Epub 2015 Sep 21.
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Roux-en-Y Gastric Bypass and Vertical Banded Gastroplasty Induce Long-Term Changes on the Human Gut Microbiome Contributing to Fat Mass Regulation.Roux-en-Y胃旁路术和垂直束带胃成形术对人体肠道微生物群产生长期影响，有助于脂肪量调节。
Cell Metab. 2015 Aug 4;22(2):228-38. doi: 10.1016/j.cmet.2015.07.009.