From the Departments of *Medical Oncology, and †Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.
Clin Nucl Med. 2017 Aug;42(8):612-614. doi: 10.1097/RLU.0000000000001724.
Lobular breast cancer is the second most common type of invasive breast cancer. Lobular breast cancer lesions are often difficult to detect with conventional imaging because they tend to grow less cohesively than ductal cancer. These images represent 3 lobular breast cancer cases, in whom confirmation of metastatic disease would make the crucial difference between curative or noncurative treatment. Staging with conventional imaging, however, yielded equivocal results, and a biopsy was not feasible. In contrast, FES (16α-[F]fluoro-17β-estradiol) PET provided a decisive contribution to clinical decision making in these patients. This indicates that FES PET may have added value in relation to conventional staging.
乳腺小叶癌是第二常见的浸润性乳腺癌类型。乳腺小叶癌病变通常很难用常规成像检测到，因为它们的生长方式不如导管癌那样具有凝聚力。这些图像代表了 3 例乳腺小叶癌患者，在这些患者中，转移性疾病的确诊将对治愈性或非治愈性治疗产生至关重要的影响。然而，常规成像分期的结果模棱两可，且活检不可行。相比之下，FES（16α-[F]氟-17β-雌二醇）PET 为这些患者的临床决策提供了决定性的帮助。这表明 FES PET 在常规分期方面可能具有附加价值。
