Orbán-Gyapai Orsolya, Forgo Peter, Hohmann Judit, Vasas Andrea
Department of Pharmacognosy, University of Szeged , H-6720 Szeged , Hungary.
Interdisciplinary Centre of Natural Products, University of Szeged , H-6720 Szeged , Hungary.
Acta Biol Hung. 2017 Jun;68(2):232-236. doi: 10.1556/018.68.2017.2.10.
In the course of our pharmacological screening of Polygonaceae species occurring in the Carpathian Basin the extracts prepared from the roots of Rumex thyrsiflorus showed promising antiproliferative, xanthine oxidase inhibitory and antibacterial activities. The present work deals with the isolation of compounds from the root of the plant. After multistep separation process, four compounds were obtained from the n-hexane, chloroform and ethyl acetate soluble fractions of the methanol extract of the root. The structures of the isolated compounds were determined as 1-palmitoylglycerol, β-sitosterol, (-)-epicatechin, and procyanidin B5.
在对喀尔巴阡盆地生长的蓼科植物进行药理筛选的过程中，从酸模的根部制备的提取物显示出有前景的抗增殖、黄嘌呤氧化酶抑制和抗菌活性。目前的工作涉及从该植物根部分离化合物。经过多步分离过程，从根部甲醇提取物的正己烷、氯仿和乙酸乙酯可溶部分获得了四种化合物。分离出的化合物结构被确定为1-棕榈酰甘油、β-谷甾醇、（-）-表儿茶素和原花青素B5。
