Gustavsen M W, Celius E G, Winsvold B S, Moen S M, Nygaard G O, Berg-Hansen P, Lie B A, Zwart J-A, Harbo H F
Department of Neurology, Oslo University Hospital, Norway.
Department of Medical Genetics, University of Oslo and Oslo University Hospital, Norway.
Mult Scler J Exp Transl Clin. 2016 Dec 12;2:2055217316682976. doi: 10.1177/2055217316682976. eCollection 2016 Jan-Dec.
Inconsistent results have been obtained with regard to headache comorbidity in multiple sclerosis (MS).
Investigate the one-year prevalence of migraine and tension-type headache (TTH) in Norwegian MS patients and relate this to clinical parameters.
A questionnaire concerning headache was administered to 756 MS patients and 1090 controls and used to determine the one-year prevalence of migraine and frequent TTH.
No significant differences were seen between patients and controls or between patients with different disease course. Less migraine was observed in patients with Expanded Disability Status Scale score (EDSS) ≥4.0.
This case-control study does not support an association between migraine or TTH and MS.
关于多发性硬化症（MS）中的头痛合并症，已获得不一致的结果。
调查挪威MS患者中偏头痛和紧张型头痛（TTH）的一年患病率，并将其与临床参数相关联。
对756例MS患者和1090例对照进行了关于头痛的问卷调查，以确定偏头痛和频繁TTH的一年患病率。
患者与对照之间或不同病程的患者之间未观察到显著差异。扩展残疾状态量表评分（EDSS）≥4.0的患者中偏头痛较少。
这项病例对照研究不支持偏头痛或TTH与MS之间存在关联。
