Smith G B, Hughes D G, Kumar V
Anaesthesia. 1985 Apr;40(4):368-71. doi: 10.1111/j.1365-2044.1985.tb10792.x.
Forty-seven children aged between four and 11 years received temazepam 0.5 mg/kg in a novel fast dispensing dosage form. The preparation was well accepted and associated with few side-effects. Satisfactory sedation and anxiolysis was obtained in over 93% of patients. The relative merits of a variety of routes of administration of premedicant drugs for children are discussed and the advantages of buccally administered formulations for this age group are presented.
47名年龄在4至11岁之间的儿童接受了新型快速给药剂型的替马西泮，剂量为0.5毫克/千克。该制剂耐受性良好，副作用较少。超过93%的患者获得了满意的镇静和抗焦虑效果。文中讨论了多种儿童术前用药给药途径的相对优缺点，并介绍了该年龄组口腔给药制剂的优势。
