实验动物咬伤过敏反应：全国性调查：第 2 部分：治疗方案。
Laboratory Animal Bite Anaphylaxis: A National Survey: Part 2: Treatment Protocols.
机构信息
Division of Occupational and Environmental Medicine, Department of Community and Family Medicine, Duke University Medical Center, Durham, North Carolina.
出版信息
J Occup Environ Med. 2017 Aug;59(8):739-741. doi: 10.1097/JOM.0000000000001063.
OBJECTIVE
This study documents current treatment protocols for laboratory animal bite anaphylaxis in the United States.
METHODS
An online survey was e-mailed to designated institutional officials at laboratory animal facilities identified by the National Institutes of Health Office of Laboratory Animal Welfare.
RESULTS
One hundred eighty-nine organizations responded to the question of whether they had a treatment protocol with 32% indicating that they had a protocol. Having a case of anaphylaxis increased the likelihood of having a protocol (61%). Of those with a protocol, 58% included treatment with injectable epinephrine, if clinically indicated. Among all respondents, only 14% reported keeping injectable epinephrine at the location where animal work is performed.
CONCLUSIONS
A minority of responding organizations had protocols in place to address laboratory animal bite anaphylaxis. Organizations with workers at risk should consider implementing a protocol for assessment and treatment.
目的
本研究记录了美国目前针对实验动物咬伤过敏反应的治疗方案。
方法
通过电子邮件向美国国立卫生研究院实验动物福利办公室确定的实验动物设施的指定机构官员发送了在线调查。
结果
189 个组织对他们是否有治疗方案的问题做出了回应，其中 32%表示他们有方案。出现过敏反应病例的机构更有可能制定方案（61%）。在有方案的机构中，58%如果临床指征明确，包括使用注射用肾上腺素进行治疗。在所有的受访者中，只有 14%报告在进行动物工作的地方备有注射用肾上腺素。
结论
回应的组织中只有少数制定了针对实验动物咬伤过敏反应的方案。有工作人员面临风险的机构应考虑制定评估和治疗方案。
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