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Pre-natal administration of diazepam improves radial maze learning in mice.

作者信息

Benton D, Dalrymple-Alford J C, Brain P F, Grimm V

出版信息

Comp Biochem Physiol C Comp Pharmacol Toxicol. 1985;80(2):273-5. doi: 10.1016/0742-8413(85)90055-6.

DOI:10.1016/0742-8413(85)90055-6
PMID:2861008
Abstract

A number of studies have found that the peri-natal exposure of rodents to diazepam alters their adult behaviour. Adult male mice, treated with diazepam or appropriate controls during pregnancy, were examined in terms of their ability to learn a radial maze. Those animals receiving diazepam prior, but not after birth, learnt the maze significantly more rapidly. The results are discussed in terms of the possible involvement of the hippocampus in this influence of diazepam.

摘要

相似文献

1
Pre-natal administration of diazepam improves radial maze learning in mice.
Comp Biochem Physiol C Comp Pharmacol Toxicol. 1985;80(2):273-5. doi: 10.1016/0742-8413(85)90055-6.
2
Modification of ovine fetal respiratory-like activity by chronic diazepam administration.长期给予地西泮对绵羊胎儿类似呼吸活动的影响。
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Obstet Gynecol. 1980 Oct;56(4):471-4.
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Some effects of diazepam on pregnancy in the Balb/C mouse.地西泮对Balb/C小鼠孕期的某些影响。
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Diazepam impairs place learning in native but not in maze-experienced rats in the Morris water maze.地西泮会损害正常大鼠在莫里斯水迷宫中的位置学习能力,但不会损害有迷宫经验大鼠的该能力。
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Effects on the offspring of chronic low exposure carbon monoxide during mice pregnancy.小鼠孕期长期低剂量接触一氧化碳对后代的影响。
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[Diazepam (Relanium)--current views on its action with special reference to developmental age].[地西泮(利眠宁)——关于其作用的当前观点,特别提及发育年龄]
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An ethological analysis of the influence of perinatally-administered diazepam on murine behaviour.围产期给予地西泮对小鼠行为影响的行为学分析
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Effects of diazepam on uteroplacental and fetal hemodynamics and metabolism.地西泮对子宫胎盘及胎儿血流动力学和代谢的影响。
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[Diazepam in obstetrics].[地西泮在产科中的应用]
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