Larra Mauro F, Behrje Andreas, Finke Johannes B, Blumenthal Terry D, Schächinger Hartmut
Department of Clinical Psychophysiology, Institute of Psychobiology, University of Trier, 54290 Trier, Germany.
Department of Clinical Psychophysiology, Institute of Psychobiology, University of Trier, 54290 Trier, Germany.
Neurosci Lett. 2017 Jul 27;654:33-37. doi: 10.1016/j.neulet.2017.06.011. Epub 2017 Jun 10.
Trace eyeblink conditioning is used as a translational model of declarative memory but restricted to the temporal domain. Potential spatial aspects have never been experimentally addressed. We employed a spatiotemporal trace eyeblink conditioning paradigm in which a spatial dimension (application side of the unconditioned stimulus) was differentially coded by tone frequency of the conditioned stimulus and recorded conditioned reactions from both eyes. We found more and stronger conditioned reactions at the side predicted by the conditioned stimulus but only in aware participants. Thus, spatial effects are present in trace eyeblink conditioning and may be differentially conditioned depending on the awareness about the spatial relation between conditioned and unconditioned stimulus.
痕迹性眨眼条件反射被用作陈述性记忆的转化模型，但仅限于时间领域。潜在的空间方面从未得到过实验研究。我们采用了一种时空痕迹性眨眼条件反射范式，其中空间维度（无条件刺激的施加侧）由条件刺激的音调频率进行差异编码，并记录双眼的条件反应。我们发现，在条件刺激预测的一侧出现了更多且更强的条件反应，但仅在有意识的参与者中如此。因此，痕迹性眨眼条件反射中存在空间效应，并且可能根据对条件刺激和无条件刺激之间空间关系的意识而产生差异条件作用。
