上消化道癌的寡转移疾病——如何应对？
Oligometastatic Disease in Upper Gastrointestinal Cancer - How to Proceed?
作者信息
Chiapponi Costanza, Berlth Felix, Plum Patrick S, Betzler Christopher, Stippel Dirk L, Popp Felix, Bruns Christiane J
机构信息
Department of General, Visceral and Cancer Surgery, University of Cologne, Cologne, Germany.
出版信息
Visc Med. 2017 Mar;33(1):31-34. doi: 10.1159/000455683. Epub 2017 Feb 15.
BACKGROUND
In the present study we review and discuss the current evidence and suggest how to proceed in the management of oligometastatic disease in upper gastrointestinal cancer.
METHODS
An electronic search of the PubMed database for relevant articles was performed.
RESULTS
Both the search for 'oligometastasis', 'oligometastases', 'oligometastatic', 'oligometastatic disease' as well as 'esophageal' and 'esophageal cancer' and the search for 'oligometastasis', 'oligometastases', 'oligometastatic', 'oligometastatic disease' as well as 'gastric', 'gastric cancer', 'stomach', and 'stomach cancer' yielded very few studies. Most data need to be extrapolated in general studies on oligometastatic diseases of different origins. No randomized controlled trial could be found.
CONCLUSION
In the absence of data to formulate recommendations on how to proceed in the treatment of oligometastatic disease in upper gastrointestinal cancer, a more aggressive treatment of oligometastatic disease can be considered in patients whose tumors show a more favorable neoplastic behavior after the 'test of time'. The RENAISSANCE study will certainly deliver important data regarding this aspect.
背景
在本研究中，我们回顾并讨论了当前的证据，并就如何处理上消化道癌的寡转移疾病提出建议。
方法
对PubMed数据库进行电子检索以查找相关文章。
结果
搜索“寡转移”“寡转移灶”“寡转移的”“寡转移疾病”以及“食管”和“食管癌”，以及搜索“寡转移”“寡转移灶”“寡转移的”“寡转移疾病”以及“胃”“胃癌”“胃”和“胃癌”，所得到的研究非常少。大多数数据需要从关于不同起源的寡转移疾病的一般研究中推断得出。未找到随机对照试验。
结论
由于缺乏关于如何处理上消化道癌寡转移疾病的推荐数据，对于肿瘤在经过“时间考验”后显示出更有利肿瘤行为的患者，可考虑对寡转移疾病采取更积极的治疗。RENAISSANCE研究肯定会提供有关这方面的重要数据。
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