Barbato F, Di Paolantonio A, Distefano M, Mastrorosa A, Sabatelli M, Servidei S, Luigetti M
Institute of Neurology, Fondazione Policlinico Universitario Agostino Gemelli, Catholic University of Sacred Heart, Rome.
Institute of Neurology, Fondazione Policlinico Universitario Agostino Gemelli, Catholic University of Sacred Heart, Rome - Fondazione Don Carlo Gnocchi, Milan, Italy.
Clin Ter. 2017 May-Jun;168(3):e208-e213. doi: 10.7417/T.2017.2008.
Miller Fisher syndrome (MFS) is considered to be an uncommon variant of Guillain-Barré Syndrome. The disease is clinically characterized by acute ataxia of limbs, areflexia and ophthalmoplegia, although the set of symptoms and signs can be quite heterogeneous, with a benign and monophasic course. We describe a case of recurrent MFS where there have been four clinical episodes occurred with complete remission after each relapse. Last recurrence was treated with oral steroids. The reported frequency of recurrent MFS in literature is variable as well as the best treatment in these cases. We add a new case treated with steroid and we perform a review of the literature.
米勒-费雪综合征（MFS）被认为是吉兰-巴雷综合征的一种罕见变异型。该疾病的临床特征为肢体急性共济失调、腱反射消失和眼肌麻痹，尽管症状和体征可能相当多样，且病程呈良性单相性。我们描述了一例复发性MFS病例，该病例已发生四次临床发作，每次复发后均完全缓解。最后一次复发采用口服类固醇治疗。文献中报道的复发性MFS的发生率各不相同，这些病例的最佳治疗方法也有所不同。我们补充了一例用类固醇治疗的新病例，并对文献进行了综述。
