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用于心血管监测的灵活有机/无机混合近红外光体积描记传感器。

Flexible Organic/Inorganic Hybrid Near-Infrared Photoplethysmogram Sensor for Cardiovascular Monitoring.

机构信息

Department of Electronic Engineering, The Chinese University of Hong Kong, New Territories, Hong Kong SAR, China.

出版信息

Adv Mater. 2017 Aug;29(31). doi: 10.1002/adma.201700975. Epub 2017 Jun 14.

Abstract

Wearable photoplethysmogram (PPG) sensors offer convenient and informative measurements for evaluating daily physiological states of individuals. In this work, epidermal and flexible near-infrared (NIR) PPG sensors integrating a low-power, high-sensitivity organic phototransistor (OPT) with a high-efficiency inorganic light-emitting diode are developed. By exploiting an organic bulk heterojunction active layer and a bilayer gate dielectric design, a low voltage (<3 V) operated OPT with NIR responsivity as high as 3.5 × 10 A W and noise equivalent power of 1.2 × 10 W Hz is achieved, greatly surpassing commercial available silicon-based photodetectors. In addition, the ultrathin encapsulation structure renders the device highly flexible and allows transfer printing of the device directly onto human skin. It is demonstrated that the epidermal/flexible PPG sensors are capable of continuously monitoring heart rate variability and precisely tracking the changes of pulse pressure at different postures of human subjects with the aid of electrocardiogram monitoring, exhibiting more reliable performance than commercial PPG sensors while consuming less power. The study suggests that the hybrid PPG sensor design may provide a promising solution for low-power, real-time physiological monitoring.

摘要

可穿戴式光体积描记(PPG)传感器为评估个体日常生理状态提供了便捷且信息量丰富的测量手段。在这项工作中,我们开发了一种表皮和柔性近红外(NIR)PPG 传感器,该传感器将低功耗、高灵敏度的有机光电晶体管(OPT)与高效无机发光二极管集成在一起。通过利用有机体异质结活性层和双层栅介质设计,实现了工作电压低(<3 V)、NIR 响应度高达 3.5×10 A W 和噪声等效功率为 1.2×10 W Hz 的 OPT,远远超过了商业上可用的硅基光电探测器。此外,该传感器的超薄封装结构使其具有高度的柔韧性,并允许将器件直接转移打印到人体皮肤上。研究表明,表皮/柔性 PPG 传感器能够借助心电图监测连续监测心率变异性,并精确跟踪人体不同姿势下的脉搏压力变化,其性能比商业 PPG 传感器更可靠,同时功耗更低。该研究表明,混合 PPG 传感器设计可能为低功耗、实时生理监测提供一种有前途的解决方案。

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