Thomas Jayakar, Kandhari Sanjiv, Oberoi Chetan, Jayaseelan Elizabeth, Raj K Yogi
Department of Dermatology, Thanjavur Medical College, Thanjavur 613004, India.
Department of Dermatology, Batra Hospital, New Delhi, India.
Indian J Dermatol Venereol Leprol. 2001 May-Jun;67(3):135-137.
The aim of this study was to compre the efficacy and safety of topical clobetasol propionate and clobetasol propionate with zinc sulphate cream preparation. Steroid responsive dermatoses were primarily considered in both the treatment groups. From thc analysis of 291 patients, from five different centres, it wasnoted that though the out come was Positive in both the trial groups significant differences existed in the treatment group which received clobetasol propionate with zinc sulphate preparation. During evaluation the outcome was even between both treatment groups on the day 7. However towards the end of the study significant differences existed. Interestingly both the treatment groups did not have any adverse effects.
本研究的目的是比较外用丙酸氯倍他索和丙酸氯倍他索硫酸锌乳膏制剂的疗效和安全性。两个治疗组主要考虑的是类固醇反应性皮肤病。通过对来自五个不同中心的291名患者的分析，注意到虽然两个试验组的结果都是阳性的，但接受丙酸氯倍他索硫酸锌制剂的治疗组存在显著差异。在评估期间，第7天时两个治疗组的结果相当。然而，在研究结束时存在显著差异。有趣的是，两个治疗组均未出现任何不良反应。
