文献检索文档翻译深度研究
Suppr Zotero 插件Zotero 插件
邀请有礼套餐&价格历史记录

新学期,新优惠

限时优惠:9月1日-9月22日

30天高级会员仅需29元

1天体验卡首发特惠仅需5.99元

了解详情
不再提醒
插件&应用
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
高级版
套餐订阅购买积分包
AI 工具
文献检索文档翻译深度研究
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2025

用于经导管原生二尖瓣置换术程序规划的3D打印心脏模型

3D Printed Cardiac Phantom for Procedural Planning of a Transcatheter Native Mitral Valve Replacement.

作者信息

Izzo Richard L, O'Hara Ryan P, Iyer Vijay, Hansen Rose, Meess Karen M, Nagesh S V Setlur, Rudin Stephen, Siddiqui Adnan H, Springer Michael, Ionita Ciprian N

机构信息

The Jacobs Institute, 875 Ellicott Street, 5 Floor, Buffalo, NY.

Biomedical Engineering, University at Buffalo, 332 Bonner Hall, Buffalo, NY.

出版信息

Proc SPIE Int Soc Opt Eng. 2016 Feb 27;9789. doi: 10.1117/12.2216952. Epub 2016 Apr 5.


DOI:10.1117/12.2216952
PMID:28615797
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5467736/
Abstract

UNLABELLED: 3D printing an anatomically accurate, functional flow loop phantom of a patient's cardiac vasculature was used to assist in the surgical planning of one of the first native transcatheter mitral valve replacement (TMVR) procedures. CTA scans were acquired from a patient about to undergo the first minimally-invasive native TMVR procedure at the Gates Vascular Institute in Buffalo, NY. A python scripting library, the Vascular Modeling Toolkit (VMTK), was used to segment the 3D geometry of the patient's cardiac chambers and mitral valve with severe stenosis, calcific in nature. A stereolithographic (STL) mesh was generated and AutoDesk Meshmixer was used to transform the vascular surface into a functioning closed flow loop. A Stratasys Objet 500 Connex3 multi-material printer was used to fabricate the phantom with distinguishable material features of the vasculature and calcified valve. The interventional team performed a mock procedure on the phantom, embedding valve cages in the model and imaging the phantom with a Toshiba Infinix INFX-8000V 5-axis C-arm bi-Plane angiography system. RESULTS: After performing the mock-procedure on the cardiac phantom, the cardiologists optimized their transapical surgical approach. The mitral valve stenosis and calcification were clearly visible. The phantom was used to inform the sizing of the valve to be implanted. CONCLUSION: With advances in image processing and 3D printing technology, it is possible to create realistic patient-specific phantoms which can act as a guide for the interventional team. Using 3D printed phantoms as a valve sizing method shows potential as a more informative technique than typical CTA reconstruction alone.

摘要

未标注:通过3D打印患者心脏血管系统的解剖学精确、功能性血流环模型,辅助了首例经导管二尖瓣置换术(TMVR)的手术规划。CTA扫描取自纽约州布法罗市盖茨血管研究所一名即将接受首例微创经导管二尖瓣置换术的患者。使用Python脚本库——血管建模工具包(VMTK),对患者严重狭窄、钙化的心脏腔室和二尖瓣的三维几何结构进行分割。生成了立体光刻(STL)网格,并使用AutoDesk Meshmixer将血管表面转化为功能性闭合血流环。使用Stratasys Objet 500 Connex3多材料打印机制作具有血管系统和钙化瓣膜可区分材料特征的模型。介入团队在模型上进行了模拟手术,将瓣膜笼嵌入模型,并使用东芝Infinix INFX - 8000V 5轴C臂双平面血管造影系统对模型进行成像。 结果:在心脏模型上进行模拟手术后,心脏病专家优化了经心尖手术入路。二尖瓣狭窄和钙化清晰可见。该模型用于确定待植入瓣膜的尺寸。 结论:随着图像处理和3D打印技术的进步,有可能创建逼真的患者特异性模型,作为介入团队的指导。使用3D打印模型作为瓣膜尺寸确定方法,显示出比单独的典型CTA重建更具信息性的技术潜力。

相似文献

[1]
3D Printed Cardiac Phantom for Procedural Planning of a Transcatheter Native Mitral Valve Replacement.

Proc SPIE Int Soc Opt Eng. 2016-2-27

[2]
3D Printed Abdominal Aortic Aneurysm Phantom for Image Guided Surgical Planning with a Patient Specific Fenestrated Endovascular Graft System.

Proc SPIE Int Soc Opt Eng. 2017-2-11

[3]
Three-dimensional prototyping for procedural simulation of transcatheter mitral valve replacement in patients with mitral annular calcification.

Catheter Cardiovasc Interv. 2018-1-23

[4]
Pre-procedural planning of transcatheter mitral valve replacement in mitral stenosis with multi-detector tomography-derived 3D modeling and printing: a case report.

Eur Heart J Case Rep. 2020-5-10

[5]
Development of 3D Printed Mitral Valve Constructs for Transcatheter Device Modeling of Tissue and Device Deformation.

Ann Biomed Eng. 2022-4

[6]
Design Optimization for Accurate Flow Simulations in 3D Printed Vascular Phantoms Derived from Computed Tomography Angiography.

Proc SPIE Int Soc Opt Eng. 2017-2-11

[7]
Validating a prediction modeling tool for left ventricular outflow tract (LVOT) obstruction after transcatheter mitral valve replacement (TMVR).

Catheter Cardiovasc Interv. 2018-8-1

[8]
Initial Simulated FFR Investigation Using Flow Measurements in Patient-specific 3D Printed Coronary Phantoms.

Proc SPIE Int Soc Opt Eng. 2017-2-11

[9]
Transcatheter Mitral Valve Replacement: An Update on the Current Literature.

Curr Treat Options Cardiovasc Med. 2019-6-17

[10]
3D Printed Modeling of the Mitral Valve for Catheter-Based Structural Interventions.

Ann Biomed Eng. 2017-2

引用本文的文献

[1]
3D printed polymers that mimic the mechanical properties of atherosclerotic blood vessels for training models: the advantageous degradation induced by UV radiation and hydrolysis.

3D Print Med. 2025-7-2

[2]
A Radiopaque Nanoparticle-Based Ink Using PolyJet 3D Printing for Medical Applications.

3D Print Addit Manuf. 2020-12-1

[3]
SPIE Medical Imaging 50th anniversary: history of the Picture Archiving and Communication Systems Conference.

J Med Imaging (Bellingham). 2022-2

[4]
The Role of 3D Printing in Planning Complex Medical Procedures and Training of Medical Professionals-Cross-Sectional Multispecialty Review.

Int J Environ Res Public Health. 2022-3-11

[5]
Evaluation of challenges and limitations of mechanical thrombectomy using 3D printed neurovascular phantoms.

Proc SPIE Int Soc Opt Eng. 2021-2

[6]
3D Printing of Physical Organ Models: Recent Developments and Challenges.

Adv Sci (Weinh). 2021-9

[7]
Three-Dimensional Printed Anatomic Models Derived From Magnetic Resonance Imaging Data: Current State and Image Acquisition Recommendations for Appropriate Clinical Scenarios.

J Magn Reson Imaging. 2022-4

[8]
Challenges in hemodynamics assessment in complex neurovascular geometries using computational fluid dynamics and benchtop flow simulation in 3D printed patient specific phantoms.

Proc SPIE Int Soc Opt Eng. 2021-2

[9]
Development and Testing of an Ultrasound-Compatible Cardiac Phantom for Interventional Procedure Simulation Using Direct Three-Dimensional Printing.

3D Print Addit Manuf. 2020-12-1

[10]
Clinical situations for which 3D printing is considered an appropriate representation or extension of data contained in a medical imaging examination: adult cardiac conditions.

3D Print Med. 2020-9-23

本文引用的文献

[1]
Treatment Planning for Image-Guided Neuro-Vascular Interventions Using Patient-Specific 3D Printed Phantoms.

Proc SPIE Int Soc Opt Eng. 2015-2-21

[2]
Percutaneous Transcatheter Mitral Valve Replacement: Patient-specific Three-dimensional Computer-based Heart Model and Prototyping.

Rev Esp Cardiol (Engl Ed). 2015-12

[3]
Replicating Patient-Specific Severe Aortic Valve Stenosis With Functional 3D Modeling.

Circ Cardiovasc Imaging. 2015-10

[4]
Transcatheter Aortic and Mitral Valve Implantation (TAMVI) in Native Rheumatic Valves.

J Card Surg. 2015-11

[5]
First-In-Man Simultaneous Transcatheter Aortic and Mitral Valve Replacement to Treat Severe Native Aortic and Mitral Valve Stenoses.

JACC Cardiovasc Interv. 2015-8-24

[6]
Simultaneous transapical transcatheter aortic valve replacement and transcatheter mitral valve replacement for native valvular stenosis.

Catheter Cardiovasc Interv. 2016-6

[7]
Three-dimensional printing to facilitate anatomic study, device development, simulation, and planning in thoracic surgery.

J Thorac Cardiovasc Surg. 2015-1-8

[8]
Comparison of modern stroke thrombectomy approaches using an in vitro cerebrovascular occlusion model.

AJNR Am J Neuroradiol. 2015-3

[9]
Effect of injection technique on temporal parametric imaging derived from digital subtraction angiography in patient specific phantoms.

Proc SPIE Int Soc Opt Eng. 2014-3-13

[10]
Challenges and limitations of patient-specific vascular phantom fabrication using 3D Polyjet printing.

Proc SPIE Int Soc Opt Eng. 2014-3-13

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

推荐工具

医学文档翻译智能文献检索