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重症监护病房中肠内营养管患者的用药错误

Medication Errors in Patients with Enteral Feeding Tubes in the Intensive Care Unit.

作者信息

Sohrevardi Seyed Mojtaba, Jarahzadeh Mohammad Hossein, Mirzaei Ehsan, Mirjalili Mahtabalsadat, Tafti Arefeh Dehghani, Heydari Behrooz

机构信息

Department of Clinical Pharmacy, Shahid Sadoughi University of Medical Sciences and Health Services, Yazd, Iran.

Department of Anesthesiology and Critical Care, Shahid Sadoughi University of Medical Sciences and Health Services, Yazd, Iran.

出版信息

J Res Pharm Pract. 2017 Apr-Jun;6(2):100-105. doi: 10.4103/jrpp.JRPP_17_9.

Abstract

OBJECTIVE

Most patients admitted to Intensive Care Units (ICU) have problems in using oral medication or ingesting solid forms of drugs. Selecting the most suitable dosage form in such patients is a challenge. The current study was conducted to assess the frequency and types of errors of oral medication administration in patients with enteral feeding tubes or suffering swallowing problems.

METHODS

A cross-sectional study was performed in the ICU of Shahid Sadoughi Hospital, Yazd, Iran. Patients were assessed for the incidence and types of medication errors occurring in the process of preparation and administration of oral medicines.

FINDINGS

Ninety-four patients were involved in this study and 10,250 administrations were observed. Totally, 4753 errors occurred among the studied patients. The most commonly used drugs were pantoprazole tablet, piracetam syrup, and losartan tablet. A total of 128 different types of drugs and nine different oral pharmaceutical preparations were prescribed for the patients. Forty-one (35.34%) out of 116 different solid drugs (except effervescent tablets and powders) could be substituted by liquid or injectable forms. The most common error was the wrong time of administration. Errors of wrong dose preparation and administration accounted for 24.04% and 25.31% of all errors, respectively.

CONCLUSION

In this study, at least three-fourth of the patients experienced medication errors. The occurrence of these errors can greatly impair the quality of the patients' pharmacotherapy, and more attention should be paid to this issue.

摘要

目的

大多数入住重症监护病房(ICU)的患者在使用口服药物或服用固体剂型药物方面存在问题。为这类患者选择最合适的剂型是一项挑战。本研究旨在评估有肠内喂养管或吞咽问题的患者口服给药错误的频率和类型。

方法

在伊朗亚兹德的沙希德·萨杜基医院ICU进行了一项横断面研究。评估患者在口服药物制备和给药过程中发生的用药错误的发生率和类型。

结果

94名患者参与了本研究,观察到10250次给药。在所研究的患者中总共发生了4753次错误。最常用的药物是泮托拉唑片、吡拉西坦糖浆和氯沙坦片。共为患者开具了128种不同类型的药物和9种不同的口服制剂。116种不同的固体药物(泡腾片和散剂除外)中有41种(35.34%)可以用液体或注射剂型替代。最常见的错误是给药时间错误。剂量准备错误和给药错误分别占所有错误的24.04%和25.31%。

结论

在本研究中,至少四分之三的患者经历了用药错误。这些错误的发生会极大地损害患者药物治疗的质量,应更加关注这个问题。

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